Evidence map›Paper›PMID 40989766›Full record

ArticleCraniomaxillofacial trauma & reconstruction2025

Impact of Therapeutic Alcohol Administration on Perioperative Quality of Life (QoL) and Fracture Healing in Patients with Alcohol Use Disorder Undergoing Surgery for Maxillofacial Trauma-A Randomized Pilot Trial.

Elavenil Panneerselvam, Rajkumar Krishnan, Jaikumar Velayudham

Abstract read
In one paragraph

Article in Craniomaxillofacial trauma & reconstruction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elavenil PanneerselvamDepartment of Oral & Maxillofacial Surgery, SRM Dental College, SRM Institute of Science & Technology, Ramapuram Campus, Chennai 600089, India.ORCID https://orcid.org/0000-0002-9930-3292
Rajkumar KrishnanDepartment of Oral & Maxillofacial Pathology & Microbiology, SRM Dental College, SRM Institute of Science & Technology, Ramapuram Campus, Chennai 600089, India; dean.acad@dental.srmrmp.edu.in.
Jaikumar VelayudhamDepartment of Psychiatry, Government Medical College, Vellore 632011, India; maildrjai@rediffmail.com.ORCID https://orcid.org/0009-0009-0939-3342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol Use Disorder (AUD) is common among patients with maxillofacial trauma. Conventional perioperative care recommends complete abstinence. However, abrupt cessation can lead to Alcohol Withdrawal Syndrome (AWS), negatively impacting psychological well-being and compliance. This randomized controlled pilot study evaluated the effectiveness of Monitored Therapeutic Alcohol Administration (MTAA) in reducing perioperative stress and enhancing quality of life without impairing fracture healing. Twenty-four adult male patients with AUD and isolated facial fractures requiring surgery were enrolled. They were assigned to either an intervention group (n = 12) receiving MTAA-oral alcohol at 0.5 g/kg/day for two weeks-or a control group (n = 12) undergoing complete abstinence. Outcomes were assessed over six weeks, including stress (Zung Self-Rating Depression Scale), quality of life (Oral Health Impact Profile-14), soft tissue healing (Landry's Index), and hard tissue healing (Moed's Scale, serum osteocalcin). The MTAA group showed significantly reduced stress and improved quality of life (

Indexed as

alcohol abusealcohol dependencealcohol use disorderalcohol withdrawal syndromemaxillofacial traumaperioperative carequality of life

Identifiers

PMID40989766
PMCPMC12452396

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.