Evidence map›Paper›PMID 40989760›Full record

ArticleBrain & spine2025

Resource use and in-hospital costs after aneurysmal subarachnoid hemorrhage in the Netherlands.

F P Mulder, J T J M van Dijck, R J G Vreeburg, C Engels, W A Moojen

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PubMed Full text at PMC Publisher
In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

F P MulderDepartment of Neurosurgery Leiden University Medical Center, Haaglanden Medical Center, Haga Teaching Hospital, University Neurosurgical Center Holland, Leiden and The Hague, the Netherlands.
J T J M van DijckDepartment of Neurosurgery Leiden University Medical Center, Haaglanden Medical Center, Haga Teaching Hospital, University Neurosurgical Center Holland, Leiden and The Hague, the Netherlands.
R J G VreeburgDepartment of Neurosurgery Leiden University Medical Center, Haaglanden Medical Center, Haga Teaching Hospital, University Neurosurgical Center Holland, Leiden and The Hague, the Netherlands.
C EngelsDepartment of Interventional Radiology, Haaglanden Medical Center, The Hague, the Netherlands.
W A MoojenDepartment of Neurosurgery Leiden University Medical Center, Haaglanden Medical Center, Haga Teaching Hospital, University Neurosurgical Center Holland, Leiden and The Hague, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Aneurysmal Subarachnoid Hemorrhage (aSAH) is a severe condition requiring advanced interventions and intensive in-hospital care. The associated financial burden challenges resource allocation and healthcare sustainability. Research question: This study aimed to evaluate the in-hospital healthcare consumption and costs for patients hospitalised with aSAH. Material and methods: A bottom-up approach was used to assess in-hospital healthcare consumption and costs for aSAH patients at a Dutch referral centre (November 2021-April 2024). Costs were calculated by multiplying resource consumption, extracted from electronic health records, by national reference prices, reflecting actual hospital costs rather than reimbursements or billing. A generalized linear model was used to identify key cost determinants. Results: A total of 147 patients were included. Mean age was 61 (±12) and 72.8 % was female. Median total costs were €31,666 (IQR: €24,167-€50,367) and length of stay was 15 days (IQR: 12-22). Total costs did not differ significantly between clipping (€28,058 (IQR: €24,167-€49,421) and coiling (€30,209 (IQR: €25,482-€50,678). However, procedure costs differed significantly between clipping (€5135 (IQR: €4886-€6000) and coiling (€7159 (IQR: €5583-€8700). The generalized linear model identified World Federation of Neurosurgical Societies grade, length of stay and delayed cerebral ischemia as key determinants of hospital costs. Discussion and conclusion: In-hospital costs for aSAH patients are substantial, with length of stay, disease severity and complications as key cost drivers. Total in-hospital costs were comparable between clipping and coiling, but procedure-specific costs varied significantly. Understanding cost distribution and cost drivers can support more efficient resource allocation and ultimately improve the cost-effectiveness of aSAH care.

Indexed as

Aneurysmal subarachnoid hemorrhageCost-driving factorsHealthcare resource consumptionIn-hospital costsRuptured intracranial aneurysm

Identifiers

PMID40989760
PMCPMC12451355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.