ArticleFrontiers in human neuroscience2025
The effect of extended early rehabilitation on the treatment outcome of patients with moderate and severe traumatic brain injury.
Article in Frontiers in human neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Functional recovery of patients with moderate and severe traumatic brain injury after extended and standard early rehabilitation.Frontiers in human neuroscience · 2026Article
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7 authors.
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Abstract
Introduction: Traumatic brain injury (TBI) is one of the leading causes of morbidity, disability and mortality in all age groups. The functional disability left by TBI, is significant for the patient, family and society. Treatment and early rehabilitation are crucial to the overall level of recovery. Objective: To compare the impact of extended early rehabilitation of patients with moderate and severe traumatic brain injury on the outcome of treatment. Material: A prospective experimental study comprised 124 patients with moderate and severe TBI, randomly divided into two groups. The patients of the experimental group had kinesitherapy seven days a week, twice a day for 45 min, and the patients of the control group had kinesitherapy seven days a week, twice a day for 30 min. The follow-up parameters were: age, sex, mechanism of injury, associated injuries, comorbidities, Glasgow Coma Scale (GCS) on admission and discharge, early rehabilitation interruptions, presence of tracheostomy, decubitus ulcers, nasogastric tube, diapers and urinary catheter at the discharge from the Intensive Care Unit and discharge from the hospital, and mortality. Results: 124 patients were randomly divided into two groups of 62 patients each. The male gender dominated 95 (76.6%). The average age was Me = 62.00 (IQR = 36.0) years. There was no statistically significant difference between the groups in gender, age, mechanism of injury, associated injuries and comorbidities. GCS on admission; 68 (54.8%) patients had severe, 56 (46.2%) moderate TBI, at discharge: 22 (17.7%) had severe, 11 (8.9%) moderate and 91 (73.4%) mild TBI. At discharge from the ICU, the presence of tracheostomy was (13 vs. 19), ( Conclusion: Extended early TBI rehabilitation is safe, effective and contributes to a positive outcome of treatment.
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