Evidence map›Paper›PMID 40989648›Full record

ArticleReproductive medicine and biology

Histopathological Association Between Chronic Endometritis and Adenomyosis: Clinical Findings and Risk Factors.

Batuhan Aslan, Cevriye Cansız Ersöz, Yavuz Emre Şükür, Batuhan Özmen, Murat Sönmezer, Bülent Berker, Ruşen Aytaç, Cem Somer Atabekoğlu

Abstract read
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Batuhan AslanDepartment of Obstetrics and Gynecology Ankara University School of Medicine Ankara Turkey.ORCID https://orcid.org/0000-0002-0785-0919
Cevriye Cansız ErsözDepartment of Pathology Ankara University School of Medicine Ankara Turkey.
Yavuz Emre ŞükürDepartment of Obstetrics and Gynecology Ankara University School of Medicine Ankara Turkey.ORCID https://orcid.org/0000-0003-0815-3522
Batuhan ÖzmenDepartment of Obstetrics and Gynecology Ankara University School of Medicine Ankara Turkey.
Murat SönmezerDepartment of Obstetrics and Gynecology Ankara University School of Medicine Ankara Turkey.
Bülent BerkerDepartment of Obstetrics and Gynecology Ankara University School of Medicine Ankara Turkey.
Ruşen AytaçDepartment of Obstetrics and Gynecology Ankara University School of Medicine Ankara Turkey.
Cem Somer AtabekoğluDepartment of Obstetrics and Gynecology Ankara University School of Medicine Ankara Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the histopathological association between chronic endometritis (CE) and adenomyosis, focusing on basal endometrial alterations and the potential involvement of tissue injury and repair (TIAR) mechanisms. Methods: This retrospective case-control study included 146 propensity score-matched hysterectomy specimens (73 adenomyosis, 73 controls). CE was diagnosed via CD38 immunohistochemical staining, identifying ≥ 5 plasma cells per high-power field. Basal endometrial thickness was measured digitally at the endo-myometrial junction. Basal endometrial loss was defined as the absence of the basal layer in at least two of three regions. Results: CE was significantly more frequent in the adenomyosis group (23.3%) than in controls (9.6%; Conclusions: CE is significantly associated with adenomyosis. Basal endometrial loss may mediate this relationship through TIAR-related mechanisms, suggesting CE as a potential therapeutic target in adenomyosis.

Indexed as

abnormal uterine bleedingadenomyosisCD38chronic endometritisimmunhistochemistry

Identifiers

PMID40989648
PMCPMC12451830

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.