Evidence map›Paper›PMID 40989629›Full record

ArticleOpen veterinary journal2025

A randomized clinical trial comparing intranasal lidocaine and saline prior to gastroscopy.

Elizabeth Alvey, Langdon Fielding, Dustin Dennis, Diane Rhodes, Emma Deane, Jessica Bouton

Abstract readComparative StudyRandomized Controlled Trial, Veterinary
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth AlveyLoomis Basin Equine Medical Center, Penryn, CA.
Langdon FieldingLoomis Basin Equine Medical Center, Penryn, CA.
Dustin DennisLoomis Basin Equine Medical Center, Penryn, CA.
Diane RhodesLoomis Basin Equine Medical Center, Penryn, CA.
Emma DeaneLoomis Basin Equine Medical Center, Penryn, CA.
Jessica BoutonLoomis Basin Equine Medical Center, Penryn, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Intranasal lidocaine (LID) administration is a common treatment used to facilitate the passing of endoscopes and nasogastric tubes in horses. However, no research has supported its use in equine practice. Aim: To compare patient reactivity and endoscope passage time between intranasal LID and intranasal saline prior to gastroscopy. Methods: This blinded, randomized clinical trial included 25 horses presenting for gastroscopy. Following the administration of sedation and prior to gastroscopy, 10 ml of saline (CON) was administered intranasally to 12 horses in the control group, or 10 ml of 2% LID was administered intranasally to 13 horses in the LID group. The recorded data included signalment, location of scoping (field or hospital), sedation, grade of reactivity on a 6-point scale (0 for no reactivity up to five when the scope could not be passed), and time to passage from the nares to the cardia. Results: The time to reach the cardia in the CON group was 73 (35-183) seconds, and the time to reach the cardia in the LID group was 70 (45-210) seconds ( Conclusion: This small study did not identify any significant benefit from administering intranasal LID prior to endoscope passage.

Indexed as

Anesthetics, LocalGastroscopyLidocaineSaline SolutionAdministration, IntranasalAnimalsFemaleHorsesMaleAnesthetics, LocalLidocaineSaline SolutionEndoscopyNasal passageNasogastric

Identifiers

PMID40989629
PMCPMC12451136

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.