ArticleOncoscience2025
When strokes reveal a hidden malignancy: An atypical case of metastatic colorectal cancer with extensive thromboembolism.
Article in Oncoscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
Cancer-associated thromboembolism and Trousseau's syndrome, which are paraneoplastic hypercoagulable states, are significant yet frequently underrecognized causes of cryptogenic stroke. We report a 71-year-old male who presented with recurrent embolic strokes and systemic thrombosis, later diagnosed with metastatic colorectal adenocarcinoma. Despite extensive investigations, no initial cancer-related symptoms were noted, and the diagnosis was made retrospectively after supraclavicular lymph node biopsy. The patient exhibited multi-territory infarcts, deep vein thrombosis, and renal and splenic infarcts, highlighting the aggressive thrombotic potential of malignancy-associated stroke. This case highlights the importance of early consideration of occult malignancy in cryptogenic embolic events, supporting comprehensive oncologic evaluation for unexplained hypercoagulable states.
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