ReviewRSC advances2025
Metal-organic frameworks for biomedical applications: bridging materials science and regenerative medicine.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Article
- Structure-Function Engineering of Hydrogel-MOF Polymer Composites for Regenerative Wound Dressings with Emerging Antiviral Biointerface Functions.Gels (Basel, Switzerland) · 2026Review
- Contrast Agents for Enhanced Bioimaging: A Comprehensive Review.Chembiochem : a European journal of chemical biology · 2026Review
- Cobalt Metal-organic Framework Alleviates DSS-Induced Ulcerative Colitis Via Barrier-protective and Immunomodulatory Effects.Biological trace element research · 2026Article
- Quantitative design principles for biofunctional metal-organic frameworks: Stability thresholds, biointerface energetics, and therapeutic applications.Materials today. Bio · 2026Review
- Potential of Covalent Organic Framework in Pharmacy and Biomedicine: Influence of Structure on Properties and Applications.ChemMedChem · 2026Review
- Enhancing the osteogenic potential of 3D-printed polycaprolactone/hydroxyapatite composite scaffolds via in-situ ZIF-8 surface modification.Journal of materials science. Materials in medicine · 2026Article
- Artificial Intelligence at the Intersection of Chemistry and Materials Science.AI (Basel, Switzerland) · 2026Article
- MXene- and MOF-Based Hydrogels: Emerging Platforms for Electrochemical Biosensing and Health Monitoring.Micromachines · 2026Review
- Converging chemistry and clinical orthopedics in the emerging role of MOFs in advanced bone defect repair.Theranostics · 2026Review
- Progress in the Development of Metal-Organic Frameworks (MOFs) for Medical Imaging of Tumors: Prospects and Challenges.International journal of nanomedicine · 2026Review
- Recent advances in metal-organic framework as nanocarriers for pesticide delivery.Frontiers in plant science · 2026Review
- Article
- Structural design of porous organic polymers to mitigate π-stacking-induced quenching in porphyrin/phthalocyanine photosensitizers for enhanced antibacterial activity.RSC advances · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review explores the biomedical applications of metal-organic frameworks (MOFs), focusing on their potential in bone regeneration. Due to their high porosity, tunable structures, and biocompatibility, MOFs have emerged as promising candidates for bone tissue engineering. This article discusses the synthesis and functionalization of MOFs at the micro- and nanoscale, their interactions with biological environments, and their roles in drug delivery, osteoinduction, and osteoconduction. Recent advancements in theranostic MOF-based scaffolds, which integrate both therapeutic and diagnostic functions, are also highlighted. By mimicking the natural bone architecture, these smart scaffolds promote ossification and angiogenesis while enabling targeted therapy and precision imaging. Despite their great potential, challenges such as metal toxicity, stability, and clinical translation remain. This review emphasizes the transformative role of MOFs in regenerative medicine and discusses strategies to overcome these limitations for future clinical applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.