Evidence map›Paper›PMID 40989503›Full record

ArticleFood chemistry. Molecular sciences2025

Deciphering the metabolic patterns of cashew apple ripening process: A comprehensive non-targeted metabolomics analysis.

Haijie Huang, Li Zhao, Weijian Huang, Xuejie Feng, Fuchu Hu, Ya Zhao, Huiliang Li, Yunlu Peng, Yuhan Wang, Zhongrun Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry. Molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haijie HuangKey Laboratory of Crop Gene Resources and Germplasm Enhancement in Southern China，Ministry of Agriculture and Rual Affairs，Key Laboratory of Tropical Crops Germplasm Resources Genetic Improvement and Innovation of Hainan Province, Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
Li ZhaoCollege of Science, Qiongtai Normal University, Tropical Biodiversity and Bioresource Utilization Laboratory, Qiongtai Normal University, Haikou, 571129, China.
Weijian HuangKey Laboratory of Crop Gene Resources and Germplasm Enhancement in Southern China，Ministry of Agriculture and Rual Affairs，Key Laboratory of Tropical Crops Germplasm Resources Genetic Improvement and Innovation of Hainan Province, Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
Xuejie FengInstitute of Tropical Fruit Trees, Hainan Academy of Agricultural Sciences, Key Laboratory of Genetic Resources Evaluation and Utilization of Tropical Fruits and Vegetables (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Key Laboratory of Tropical Fruit Tree Biology of Hainan Province, Haikou 571100, China.
Fuchu HuInstitute of Tropical Fruit Trees, Hainan Academy of Agricultural Sciences, Key Laboratory of Genetic Resources Evaluation and Utilization of Tropical Fruits and Vegetables (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Key Laboratory of Tropical Fruit Tree Biology of Hainan Province, Haikou 571100, China.
Ya ZhaoInstitute of Tropical Fruit Trees, Hainan Academy of Agricultural Sciences, Key Laboratory of Genetic Resources Evaluation and Utilization of Tropical Fruits and Vegetables (Co-construction by Ministry and Province), Ministry of Agriculture and Rural Affairs, Key Laboratory of Tropical Fruit Tree Biology of Hainan Province, Haikou 571100, China.
Huiliang LiInstitute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Key Laboratory for Biology and Genetic Resources of Tropical Crops of Hainan Province, Haikou,571101, China.
Yunlu PengInstitute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Key Laboratory for Biology and Genetic Resources of Tropical Crops of Hainan Province, Haikou,571101, China.
Yuhan WangHainan Key Laboratory of Storage & Processing of Fruits and Vegetables, Agricultural Products Processing Research Institute, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang 524001, China.
Zhongrun ZhangKey Laboratory of Crop Gene Resources and Germplasm Enhancement in Southern China，Ministry of Agriculture and Rual Affairs，Key Laboratory of Tropical Crops Germplasm Resources Genetic Improvement and Innovation of Hainan Province, Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
Yijun LiuHainan Key Laboratory of Storage & Processing of Fruits and Vegetables, Agricultural Products Processing Research Institute, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang 524001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolite changes during the ripening process of cashew apples are crucial for their quality development. A total of 2379 metabolites were isolated and identified from fresh cashew apples at four different ripening stages using UHPLC-MS. Metabolite set enrichment analysis (MSEA) revealed that the differential metabolites in CA2_vs_CA1, CA3_vs_CA2, and CA4_vs_CA3 comparisons were mainly enriched in amino acids and peptides, steroids, pyrimidines, and fatty acids and conjugates, etc. Volcano plot analysis identified 631, 384, and 392 upregulated metabolites, and 625, 923, and 392 downregulated metabolites in CA2_vs_CA1, CA3_vs_CA2, and CA4_vs_CA3 comparisons, respectively. KEGG pathway enrichment analysis demonstrated that these differential metabolites were primarily involved in aminoacyl-tRNA biosynthesis, purine metabolism, and glycine, etc. Notably, the differential metabolites in CA4_vs_CA3 showed the highest enrichment in d-glutamine and D-glutamate metabolism, as well as phenylalanine. The metabolic profile of cashew apples revealed stage-specific patterns during ripening, offering key insights for optimizing harvest, storage, and processing.

Indexed as

Cashew appleKEGG pathwayMaturityNon-targeted metabolome

Identifiers

PMID40989503
PMCPMC12451386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.