Evidence map›Paper›PMID 40989327›Full record

ArticlePeerJ. Computer science2025

Testing the knowledge of artificial intelligence chatbots in pharmacology: examples of two groups of drugs.

Marcin Mateusz Granat, Aleksandra Paź, Dagmara Mirowska-Guzel

Abstract read
In one paragraph

Article in PeerJ. Computer science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marcin Mateusz GranatDepartment of Clinical and Experimental Pharmacology, Medical University of Warsaw, Warsaw, Poland.
Aleksandra PaźDepartment of Clinical and Experimental Pharmacology, Medical University of Warsaw, Warsaw, Poland.
Dagmara Mirowska-GuzelDepartment of Clinical and Experimental Pharmacology, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The study aimed to evaluate eight artificial intelligence chatbots (ChatGPT-3.5, Microsoft Copilot, Gemini, You.com, Perplexity, Character.ai, Claude 3.5, and ChatRTX) in answering questions related to two pharmacological topics taught during the basic pharmacology curriculum for medical students: antifungal drugs and hypolipidemic drugs. Methods: Chatbots' performance was assessed by answering 60 single-choice questions on antifungal and hypolipidemic drugs topics. The questions were designed to have four answers (a, b, c, and d), and the artificial intelligence (AI) role was to choose the proper one. The assessment was performed twice with a 1-year hiatus to determine if artificial intelligence chatbots' effectiveness changed over time. All the answers were checked for being right or wrong according to up-to-date pharmacology knowledge. To improve the clarity of results, to each score, a mark was assigned based on the grading system applied in our unit. Statistica software version 13.3 and Microsoft Excel 2010 were used for statistical analysis. Results: In 2023, the best results on the subject of antifungal drugs were obtained by Gemini (formerly Bard) and on the topic of hypolipidemic drugs by You.com (formerly YouChat). In 2024 Microsoft Copilot answered correctly the highest number of questions in both topics. The total results of all artificial intelligence chatbots in 2023 and 2024 were compared using t-test for dependent samples. Statistical analysis revealed that artificial intelligence chatbots improved over time in both pharmacological topics, but this change was not statistically significant ( Conclusions: The accuracy of AI chatbots' responses regarding antifungal and hypolipidemic drugs improved over one year, though not significantly. None of the tested AI systems provided correct answers to all questions within these pharmacological fields.

Indexed as

AIAI chatbotsAntifungal drugsArtificial intelligenceHypolipidemic drugsPharmacology

Identifiers

PMID40989327
PMCPMC12453646

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.