Evidence map›Paper›PMID 40989185›Full record

ArticleFrontiers in cellular and infection microbiology2025

Swine influenza-modified pulmonary microbiota.

Javier Arranz-Herrero, Sara Izpura-Luis, Jesus Presa, Paloma Reche, Paloma Encinas, Taeyong Kwon, Sergio Rius-Rocabert, Vicent Tur-Planells, Juan Luis Tejerina, Jordi Ochando and 7 more

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Javier Arranz-Herrero *Microbiology Section, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Sara Izpura-Luis *Microbiology Section, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Jesus PresaIndependent Researcher, Madrid, Spain.
Paloma RecheMicrobiology Section, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Paloma EncinasDepartment of Biotechnology, National Institute of Agricultural and Food Research and Technology (INIA, CSIC), Madrid, Spain.
Taeyong KwonDepartment of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.
Sergio Rius-RocabertMicrobiology Section, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Vicent Tur-PlanellsMicrobiology Section, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Juan Luis TejerinaIndependent Researcher, Madrid, Spain.
Jordi OchandoTransplant Immunology Unit, National Center of Microbiology, Instituto de Salud Carlos III, Madrid, Spain.
César B Gutiérrez-MartínDepartment of Animal Health, Faculty of Veterinary, Universidad de León, León, Spain.
Eric BortzDepartment of Biological Sciences, University of Alaska Anchorage, Anchorage, AK, United States.
Adolfo Garcia-SastreDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Juergen A RichtDepartment of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.
Maria MontoyaViral Immunology Lab, Molecular Biomedicine Department, BICS Unit, Margarita Salas Center for Biological Research (CIB-CSIC), Madrid, Spain.
Gustavo Del RealDepartment of Biotechnology, National Institute of Agricultural and Food Research and Technology (INIA, CSIC), Madrid, Spain.
Estanislao Nistal-VillanMicrobiology Section, Departamento de Ciencias Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A virus (IAV) remains a major health concern in both humans and animals, with pigs serving as key reservoirs for generating novel reassortant viruses with pandemic potential. Respiratory microbiome alterations during infection may facilitate secondary bacterial complications. This study investigates the lung microbiota of pigs naturally infected with IAV across different regions in Spain, using Oxford Nanopore Technologies (ONT) long-read 16S rRNA sequencing to characterize associated bacterial communities. Our results show a higher bacterial genus diversity in IAV-infected animals compared to healthy controls, with significant differences in both presence and relative abundance of bacterial taxa. Infected lungs exhibited increased proportions of potential pathogens, particularly

Indexed as

BacteriaInfluenza A virusLungMicrobiotaOrthomyxoviridae InfectionsSwine DiseasesAnimalsDNA, BacterialDNA, RibosomalPhylogenyRNA, Ribosomal, 16SSequence Analysis, DNASpainSwineDNA, BacterialDNA, RibosomalRNA, Ribosomal, 16Scoinfectioninfluenza viruslungOxford Nanoporepigsrespiratory microbiomesequencingswine

Identifiers

PMID40989185
PMCPMC12450909

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.