Evidence map›Paper›PMID 40989178›Full record

ArticleFrontiers in cellular and infection microbiology2025

A novel genotype of

Wenbo Xu, Wei Wang, Liyan Sui, Nan Liu, Yinghua Zhao, Quan Liu

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wenbo XuDepartment of Infectious Diseases and Center for Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, The First Hospital of Jilin University, Changchun, China.
Wei WangHulunbuir Animal Disease Control Center, Hailar, China.
Liyan SuiDepartment of Infectious Diseases and Center for Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, The First Hospital of Jilin University, Changchun, China.
Nan LiuDepartment of Infectious Diseases and Center for Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, The First Hospital of Jilin University, Changchun, China.
Yinghua ZhaoDepartment of Infectious Diseases and Center for Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, The First Hospital of Jilin University, Changchun, China.
Quan LiuDepartment of Infectious Diseases and Center for Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, The First Hospital of Jilin University, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hepaciviruses (family Methods: In this study, metagenomic sequencing was performed on 21 serum samples collected from reindeer ( Results: Among 21 reindeer serum samples, the positivity rates of RtHepV GH01 and GH02 were 42.9% (9/21) and 4.8% (1/21), respectively. These isolates shared the highest sequence identities with the BovHepV Bulgaria 9 strain, with nucleotide identities of 68.2% (GH01) and 67.9% (GH02), and amino acid identities of 75.0% (GH01) and 74.8% (GH02). Phylogenetic analysis clustered RtHepV within the Conclusion: This study reports the identification of two novel hepacivirus variants in reindeer from northeastern China, closely related to bovine hepaciviruses. These findings expand the known host range and geographic distribution of Hepacivirus, highlighting its ecological adaptability and the risk of cross-species transmission. The results underscore the potential public and veterinary health implications of hepaciviruses, warranting further investigation into the epidemiology of hepaciviruses.

Indexed as

GenotypeHepacivirusHepatitis CReindeerAnimalsCattleChinaGenome, ViralHost SpecificityMetagenomicsPhylogenyRecombination, Geneticco-evolutionhepacivirusmetagenomic sequenceNortheastern ChinaRangifer tarandus

Identifiers

PMID40989178
PMCPMC12450936

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.