Evidence map›Paper›PMID 40989135›Full record

ArticleIranian journal of otorhinolaryngology2025

A Prospective Observational Study on the Accuracy of Transcutaneous Laryngeal Ultrasonography in Assessing Vocal Cord Mobility before and after Thyroid Surgery.

Harjinder Singh, Thirugnanasambandam Nelson, Kamal Kataria, Ankita Agarwal, Uttam Kumar Thakur, Arvind Kairo, Hitesh Verma, Shuchita Singh Pachaury, Amarinder Singh Malhi, Yashwant Rathore and 6 more

Abstract read
In one paragraph

Article in Iranian journal of otorhinolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Harjinder SinghDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Thirugnanasambandam NelsonDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Kamal KatariaDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Ankita AgarwalDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Uttam Kumar ThakurDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Arvind KairoDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, India.
Hitesh VermaDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, India.
Shuchita Singh PachauryDepartment of Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, India.
Amarinder Singh MalhiDepartment of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Yashwant RathoreDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Yashdeep GuptaDepartment of Endocrinology, All India Institute of Medical Sciences, New Delhi, India.
Shivam PandeyDepartment of Biostastics, All India Institute of Medical Sciences, New Delhi, India.
Rajesh KhadgawatDepartment of Endocrinology, All India Institute of Medical Sciences, New Delhi, India.
Shipra AgarwalDepartment of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Sunil ChumberDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
Anita DharDepartment of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Recurrent Laryngeal Nerve (RLN) injury remains one of the significant complications associated with thyroidectomy, occurring in approximately 1% to 9% of cases. Vocal Cord (VC) function is typically assessed before surgery using laryngoscopy. However, Transcutaneous Laryngeal Ultrasonography (TLUS) has become a non-invasive alternative for evaluating VC mobility. This study was performed to compare the diagnostic accuracy of TLUS with traditional laryngoscopy in assessing vocal cord function in patients undergoing thyroid surgery. Materials and Methods: A total of 105 patients undergoing hemi- or total thyroidectomy were enrolled in a prospective observational study at a tertiary healthcare facility from October 2022 to June 2024. TLUS was conducted by endocrine surgeons using a Mindray UGW 11 device. VC mobility was categorised as usual (spontaneous, rhythmic, symmetrical movement) or unilateral VC paralysis (asymmetrical or absent movement on the affected side). Results: In the preoperative setting, TLUS achieved 100% sensitivity, Positive Predictive Value (PPV), and overall diagnostic accuracy. Postoperatively, it maintained a high sensitivity of 99.02%, with specificity reaching 100% and an area under the curve (AUC) of 0.99. The PPV remained at 100%, while the Negative Predictive Value (NPV) was 75%, and the diagnostic accuracy declined slightly to 99.05%. These findings highlight TLUS as a reliable, economical, and patient-friendly modality for evaluating vocal cord mobility in thyroid surgery. Conclusion: TLUS is an effective non-invasive method for assessing VC function, with high diagnostic accuracy. With further advancements in ultrasound technology and standardized protocols, TLUS can be incorporated into routine clinical practice as a supplement to traditional laryngoscopy techniques. This study supports the use of TLUS as a viable alternative for preoperative and postoperative VC assessment in thyroid surgery patients.

Indexed as

LaryngoscopyThyroidectomyTranscutaneous Laryngeal UltrasonographyVocal Cord Function

Identifiers

PMID40989135
PMCPMC12451702

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