Evidence map›Paper›PMID 40989112›Full record

ArticleFrontiers in cardiovascular medicine2025

Cardiovascular disease in North African women: insights from the Middle East African Women CardioVascular Disease (MEA-WCVD) registry.

Salma Charfeddine, Leila Abid, Sarra Chenik, Iheb Ben Krayen, Oussama Haddar, Aymen Ghrab, Selim Boudiche, Haithem Touati, Oumaima Ayedi, Mohamed Amine Ammar and 74 more

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Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

84 authors.

Salma CharfeddineCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Leila AbidCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Sarra ChenikCardiology Department, Military University Hospital, Tunis, Tunisia.
Iheb Ben KrayenCardiology Department, Habib Bourguiba University Hospital, Medenine, Tunisia.
Oussama HaddarCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Aymen GhrabCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Selim BoudicheCardiology Department, La Rabta University Hospital, Tunis, Tunisia.
Haithem TouatiCardiology Department, Habib Bourguiba University Hospital, Medenine, Tunisia.
Oumaima AyediCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Mohamed Amine AmmarCardiology Department, Menzel Bourguiba University Hospital, Bizerte, Tunisia.
Manel Ben HalimaCardiology Department, La Rabta University Hospital, Tunis, Tunisia.
Houssem Ben AyedCardiology Department, Military University Hospital, Tunis, Tunisia.
Asma BrahimCardiology Department, La Rabta University Hospital, Tunis, Tunisia.
Faten ElAyechCardiology Department, Charles Nicolle University Hospital, Tunis, Tunisia.
Emna AlloucheCardiology Department, Charles Nicolle University Hospital, Tunis, Tunisia.
Houssem ThabetCardiology Department, Sahloul University Hospital, Sousse, Tunisia.
Houaida MahfoudhiCardiology Department, Military University Hospital, Tunis, Tunisia.
Taha Yessine JablounCardiology Department, Military University Hospital, Tunis, Tunisia.
Yasmine AyadiCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Alaeddine AyadiCardiology Department, Mongi Slim La Marsa University Hospital, Tunis, Tunisia.
Ghassen RomdhaniCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Hassen GargouriCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Oumayma ZidiCardiology Department, Abderrahman Mami University Hospital, Ariana, Tunisia.
Mohamed Ali GuedriCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Rami TliliCardiology Department, Mongi Slim La Marsa University Hospital, Tunis, Tunisia.
Bechir TrabelsiCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Selim HammamiCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Rim OthmenCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Saoussen AntitCardiology Department, FSI La Marsa University Hospital, Tunis, Tunisia.
Syrine SaidaneCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Sirine DardourCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Skander IddirCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Elmahdi KharratCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Anis CheikhrouhouCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Mohamed DerwichCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Amal MrabetCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Taha LassouedCardiology Department, Habib Bourguiba University Hospital, Medenine, Tunisia.
Emna RekikCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Sahar GmihaCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Niez LaribiCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Hakim LamineCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Zied TrikiCardiology Department, Mongi Slim La Marsa University Hospital, Tunis, Tunisia.
Samir AyariCardiology Department, Menzel Bourguiba University Hospital, Bizerte, Tunisia.
Fatma BoujelbenePrivate Cardiologist, Sfax, Tunisia.
Essia BoughzelaPrivate Cardiologist, Tunis, Tunisia.
Hajer RekikPrivate Cardiologist, Sfax, Tunisia.
Ines Ben AmeurPrivate Cardiologist, Sfax, Tunisia.
Syrine AbidPrivate Cardiologist, Tunis, Tunisia.
Khalil OueghlaniCardiology Department, Djerba Hospital, Medenine, Tunisia.
Abddayem HagguiCardiology Department, Military University Hospital, Tunis, Tunisia.
Afef Ben HalimaCardiology Department, Abderrahman Mami University Hospital, Ariana, Tunisia.
Wejdene OuechtatiCardiology Department, Charles Nicolle University Hospital, Tunis, Tunisia.
Emna BennourCardiology Department, Abderrahman Mami University Hospital, Ariana, Tunisia.
Rania HammamiCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Mariem JabeurCardiology Department, Hedi Chaker University Hospital, Sfax, Tunisia.
Ihsen ZairiCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Mariem DrissaCardiology Department, Mongi Slim La Marsa University Hospital, Tunis, Tunisia.
Faouzi AddadPrivate Cardiologist, Tunis, Tunisia.
Sami MilouchiCardiology Department, Habib Bourguiba University Hospital, Medenine, Tunisia.
Mohamed Sami MouraliCardiology Department, La Rabta University Hospital, Tunis, Tunisia.
Hedi Ben SlimaCardiology Department, Menzel Bourguiba University Hospital, Bizerte, Tunisia.
Leila BezdahCardiology Department, Charles Nicolle University Hospital, Tunis, Tunisia.
Elyes NeffatiCardiology Department, Sahloul University Hospital, Sousse, Tunisia.
Youssef Ben AmeurCardiology Department, Mongi Slim La Marsa University Hospital, Tunis, Tunisia.
Sondos KraiemCardiology Department, Habib Thameur University Hospital, Tunis, Tunisia.
Salem KachbouraCardiology Department, Abderrahman Mami University Hospital, Ariana, Tunisia.
Ikram KammounCardiology Department, Abderrahman Mami University Hospital, Ariana, Tunisia.
Lilia ZakhamaCardiology Department, FSI La Marsa University Hospital, Tunis, Tunisia.
Hassen Lbn Hadj AmorCardiology Department, Taher Sfar University Hospital, Mahdia, Tunisia.
Khaldoun Ben HamdaCardiology Department B, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Yosra MessoudiCardiology Department, Ibn El Jazzar University Hospital, Kairouan, Tunisia.
Nejah Ben HlimaCardiology Department, Ibn El Jazzar University Hospital, Kairouan, Tunisia.
Rana DahmaniCardiology Department, Military Hospital, Bizerte, Tunisia.
Habib GamraCardiology Department A, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Zied Ibn ElhadjCardiology Department, Taher Maamouri University Hospital, Nabeul, Tunisia.
Hichem DenguirCardiology Department, Gabes Hospital, Gabes, Tunisia.
Chayma GhorbelCardiology Department, Kasserine Hospital, Kasserine, Tunisia.
Nizar MechriCardiology Department, Tatouine Hospital, Tatouine, Tunisia.
Samia Ernez HajriCardiology Department, Farhat Hached University Hospital, Sousse, Tunisia.
Alexandre MebazaaDepartment of Anesthesia and Critical Care, Lariboisière Hospital, Paris, France.
Fedi Ben DhaouPreventive Department, Habib Bourguiba Hospital, Sfax Tunisia.
Maroua TriguiPreventive Department, Habib Bourguiba Hospital, Sfax Tunisia.
Wafa FehriCardiology Department, Military University Hospital, Tunis, Tunisia.
Salem AbdessalemCardiology Department, Pasteur Clinic, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) is a major health burden worldwide, yet gender-specific data from the Middle East and North Africa (MENA) region remain scarce. The Middle East African Registry of Women with Cardiovascular Disease enrolled adult patients with coronary heart disease (CHD), heart failure (HF), atrial fibrillation (AF), or valvular heart disease (VHD) across Tunisia between May and July 2023. Of 15,366 patients, 37.6% were women. Compared with men, women were older, had lower socioeconomic status, and presented with more obesity, hypertension, diabetes, dyslipidemia, and sedentary lifestyle but smoked less. CHD was less frequent in women, while AF and VHD were more prevalent. Women underwent fewer coronary angiographies and percutaneous interventions, experienced longer delays, and received fewer guideline-based therapies, including dual antiplatelet agents and high-intensity statins. Among HF patients, women more often had preserved ejection fraction and higher hospitalization rates. These results highlight persistent gender inequities in CVD care in Tunisia.

Indexed as

atrial fibrillationcardiovascular diseasecardiovascular risk factorscoronary heart diseaseheart failurevalvular heart diseasewomen

Identifiers

PMID40989112
PMCPMC12450928

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