ArticleRadiology case reports2025
Gastrointestinal stromal tumor of the rectum: A case report with emphasis on MRI-pathologic correlation.
Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
A 73-year-old male presented with a 6-month history of incomplete defecation, prompting investigation. Physical examination revealed a smooth, broad-based rectal mass located at the 12-4 o'clock position, with no mucosal ulcerations or bleeding. MRI imaging displayed a well-defined, round mass (3.5 cm × 2.8 cm) exhibiting homogeneous intermediate signals on T1-weighted imaging and hyperintensity on T2-weighted imaging, along with restricted diffusion indicated by low apparent diffusion coefficient values. Surgical intervention involved complete resection of the mass via the anus, with gross examination revealing grayish-red fragmented tissue. Histopathological assessment identified spindle cells with high mitotic activity, confirmed by immunohistochemistry as DOG-1 positive, consistent with gastrointestinal stromal tumor (GIST). Postoperative CT indicated complete resection, and at the 2-month follow-up, the patient's symptoms had resolved. This case underscores the significance of early diagnosis and surgical management of rectal GIST in patients presenting with nonspecific gastrointestinal symptoms.
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