ArticleDEN open2026
Effectiveness of Gel-immersion Endoscopic Injection Sclerotherapy Under Texture and Color Enhancement Imaging for Esophageal Varices: A Comparison of Variceal Visibility Under Gel With White Light Imaging.
Article in DEN open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Gel-immersion endoscopic injection sclerotherapy (GI-EIS) addresses the technical challenges in intravariceal injection for esophageal varices (EVs). However, gel accumulation may obscure the variceal morphology. Thus, we developed GI-EIS under texture and color enhancement imaging (TXI) and evaluated its effectiveness. Methods: This study included EV patients who underwent primary prophylactic intravariceal EIS. Patients were divided into GI-EIS under TXI and conventional EIS groups. Primary outcomes were the success rates of intravariceal sclerosant injection and sclerosant injection into the afferent vessels. Secondary outcomes included the visibility score of EV morphology under TXI compared with white light imaging (WLI) during gel-immersion and luminance gradient across the EVs. Results: Overall, 32 patients (16 in each group) were evaluated. The success rate of intravariceal sclerosant injection was comparable between GI-EIS under TXI and conventional EIS (93.8% vs. 87.5%, Conclusion: GI-EIS under TXI provided improved visualization of variceal morphology and enhanced success of injection into afferent vessels, suggesting that TXI may optimize the therapeutic performance of GI-EIS for EV.
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