Evidence map›Paper›PMID 40988969›Full record

ArticleCureus2025

Bevacizumab-Associated Enterocutaneous Fistula: A Case Report and Management Review.

Madison L Wallace, Linda Akbarshahi, Matthew Bond, Tembele Yangandawele, Thomas Howdieshell

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Madison L WallaceObstetrics and Gynecology, Medical College of Georgia, Augusta University, Athens, USA.
Linda AkbarshahiFamily Medicine, Northeast Georgia Medical Center Gainesville, Gainesville, USA.
Matthew BondSurgery, Northeast Georgia Medical Center Gainsville, Gainesville, USA.
Tembele YangandaweleFamily Medicine, Northeast Georgia Medical Center Gainsville, Gainesville, USA.
Thomas HowdieshellTrauma Surgery, Medical College of Georgia, Augusta University, Athens, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterocutaneous fistula (ECF) formation is a rare but severe complication of bevacizumab therapy. This case report documents the first known patient to develop both an ECF and a colovaginal fistula following bevacizumab treatment for recurrent cervical cancer without prior radiation therapy. A comprehensive literature review of current and nutritional management guidelines, in the context of this patient's complex condition, highlights the need for refined risk stratification and management frameworks. This report aims to contribute to the evolving understanding of bevacizumab's adverse effects and inform future therapeutic decision-making.

Indexed as

anti-vegf therapybevacizumab therapyenterocutaneous fistulafistula managementimmunotherapy side effectslocally advanced cervical cancerneoadjuvant bevacizumaboncology patientrecurrent cervical cancerrecurring cervical cancer

Identifiers

PMID40988969
PMCPMC12453002

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.