ArticleCureus2025
Patient Factors Associated With Vision Complaints in Idiopathic Intracranial Hypertension: A Cross-Sectional Study.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Idiopathic intracranial hypertension (IIH), formerly known as pseudotumor cerebri, is characterized by elevated intracranial pressure (ICP) and papilledema in the absence of focal neurological deficits or structural brain abnormalities. This study aimed to describe the demographic and clinical characteristics of a sample of patients with IIH and examine associations between visual complaints and various demographic, clinical, and ophthalmologic variables. Methods This retrospective cross-sectional study included 106 patients diagnosed with IIH in a neurology practice in the Southeast United States. Demographic data, clinical features, and ophthalmologic parameters were collected, including intraocular pressure (IOP) measurements and reports of visual complaints (blurred vision, vision loss, and transient visual obscuration). Lumbar punctures were conducted in either a seated (n=46) or lateral decubitus (n=60) position. Translaminar pressure difference (TLPD) was calculated. Chi-squared tests were used for categorical comparisons, and t-tests were used for continuous variables. Primary outcomes included the presence of visual complaints and their relationship with ICP, IOP, TLPD, and other clinical factors. Results Overall, 61% of patients reported at least one form of visual complaint, with symptom-specific prevalence ranging from 12% to 37%. In the lateral decubitus group, blurred vision occurred with higher TLPD (mean 44.0 vs 34.3, p=0.03, d=0.82). In the lateral decubitus group, blurred vision occurred with higher TLPD (mean 44.0 vs 34.3, p=0.03, Cohen's d=0.82). Vision loss occurred with lower IOP (mean 26.3 vs 36.1 mmHg, p=0.04, Cohen's d=1.09). Any vision complaint was associated with higher ICP (mean 38.0 vs 34.6 mmHg, p=0.04, Cohen's d=0.44). Conclusions IOP and TLPD showed outcome-specific associations with visual complaints, particularly blurred vision in patients sampled in lateral decubitus. These pressure measures may help risk-stratify visual symptoms in IIH and potentially warrant prospective validation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.