Evidence map›Paper›PMID 40988743›Full record

SynthesisFrontiers in medicine2025

The clinical value of acupuncture combined with Wenjing decoction in treating primary dysmenorrhea in women-a systematic review and meta-analysis of randomized controlled trials.

Mei Zhao, Fuhua Zhou, Chunmei Qiu, Xiumei Hu, Caiping Xie, Lixin Wen, Lianwei Xu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mei ZhaoSanming Hospital of Integrated Medicine, Sanming, China.
Fuhua ZhouSanming Hospital of Integrated Medicine, Sanming, China.
Chunmei QiuSanming Hospital of Integrated Medicine, Sanming, China.
Xiumei HuSanming Hospital of Integrated Medicine, Sanming, China.
Caiping XieSanming Hospital of Integrated Medicine, Sanming, China.
Lixin WenSanming Hospital of Integrated Medicine, Sanming, China.
Lianwei XuDepartment of Gynecology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To systematically evaluate the clinical efficacy of combining acupuncture and Wenjing decoction for primary dysmenorrhea (PD) of cold congealing and blood stasis type, using the meta-analysis research methods, to provide references for clinical treatment. Methods: A randomized controlled trial (RCT) on the treatment of PD using Wenjing decoction with or without acupuncture was searched across multiple databases from 1 January 2000 to 1 March 2025. Outcome measurements included serum hormone levels, pain scores, uterine artery blood flow, and overall effectiveness rate. The quality of the studies included was assessed using the risk of bias tool. The methodological quality of the included studies was assessed with the Cochrane Collaboration tool. Review Manager 5.4 software was employed for quantitative synthesis, and funnel plots were utilized to evaluate potential reporting bias. Results: A total of 11 RCTs with 1,024 patients with primary dysmenorrhea were included. Wenjing decoction combined with acupuncture in the treatment of PD has obvious advantages over the control group in improving the effective rate [relative risk (RR) = 1.24], [95% confidence interval (CI): (1.06, 1.42), I Conclusion: The combination of acupuncture and Wenjing decoction in the treatment of primary dysmenorrhea (PD) is superior to simple Western medicine treatment in reducing the level of prostaglandin F2 alpha (PGF Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42024623207.

Indexed as

acupuncture therapyintegrative medicinemeta-analysisprimary dysmenorrheaWenjing decoction

Identifiers

PMID40988743
PMCPMC12450975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.