Evidence map›Paper›PMID 40988717›Full record

ArticleTherapeutic advances in pulmonary and critical care medicine

Point-of-Care Ultrasound Evaluation of Diaphragm as a Predictor of Extubation Success in Mechanically Ventilated, Malnourished, End-Stage Liver Disease Pretransplant Candidates-Observational Cohort Study.

Adam Muhammad Reid, Sarathi Bhattacharyya, Zian Zhuang, Nida Qadir, Amy Schnabel, Alan Chiem, Semi Yoon, George Lim, Igor Barjaktarevic

Abstract read
In one paragraph

Article in Therapeutic advances in pulmonary and critical care medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adam Muhammad ReidDepartment of Internal Medicine, Jefferson Einstein Philadelphia Hospital, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-9550-2593
Sarathi BhattacharyyaDepartment of Medicine, Long Beach Memorial Medical Center, Long Beach, California, USA.
Zian ZhuangDepartment of Biostatistics, Fielding School of Public Health at UCLA, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-6332-194X
Nida QadirDivision of Pulmonary, Critical Care, and Sleep Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Amy SchnabelClinical Nutrition, Liver Transplant service, Ronald Reagan Medical Center at UCLA, Los Angeles, CA, USA.
Alan ChiemDepartment of Emergency Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Semi YoonDivision of Pulmonary, Critical Care, and Sleep Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
George LimDepartment of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Igor BarjaktarevicDivision of Pulmonary, Critical Care, and Sleep Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-8096-0858

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ultrasound evaluation of diaphragmatic anatomy and function has recently gained traction as a simple and useful tool to assess the extubation readiness in mechanically ventilated patients, nevertheless, how applicable this approach is in the population of chronically debilitated patients on mechanical ventilation (MV) remains unclear. Objective: To evaluate ultrasonographic assessment of diaphragmatic thickening fraction (ΔTDI%) as a predictor of extubation success in the population of end-stage liver disease (ESLD) malnourished patients on MV. Design: Prospective, single-center, observational cohort study. Methods: We used point-of-care ultrasound to evaluate ΔTDI% and diaphragm thickness during expiration ( Results: Of 70 enrolled patients, 82.4% ( Conclusion: Point-of-care ultrasonographic assessment of the diaphragm offers insight into the function of respiratory muscles and the limited ability to predict extubation success. Further research is necessary to better understand its potential use in MV liberation in patients with ESLD and malnutrition.

Indexed as

cirrhosisdebilitateddiaphragm thickening fractionend-stage liver diseaseextubation failuremalnourishedPOCUSultrasoundweaning from mechanical ventilation

Identifiers

PMID40988717
PMCPMC12451113

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.