Evidence map›Paper›PMID 40988708›Full record

ArticleToxicology reports2025

The

Piper Reid Hunt, Nicholas Olejnik, Jeffrey Yourick, Robert L Sprando

Abstract read
In one paragraph

Article in Toxicology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. High-Throughput Toxicity Screening withEnvironmental science & technology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Piper Reid HuntDivision of Toxicology, Human Foods Program, U.S. Food and Drug Administration, Laurel, MD 20708, United States.
Nicholas OlejnikDivision of Toxicology, Human Foods Program, U.S. Food and Drug Administration, Laurel, MD 20708, United States.
Jeffrey YourickDivision of Toxicology, Human Foods Program, U.S. Food and Drug Administration, Laurel, MD 20708, United States.
Robert L SprandoDivision of Toxicology, Human Foods Program, U.S. Food and Drug Administration, Laurel, MD 20708, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developmental delay and spontaneous locomotor activity changes, as well as the reversibility of these adverse effects are apical endpoints used in chemical safety evaluations. These endpoints were assessed at sublethal concentrations in

Indexed as

Alternative toxicity test methodChemical screeningDevelopmental toxicityLocomotor activitySmall model organism

Identifiers

PMID40988708
PMCPMC12451289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.