Evidence map›Paper›PMID 40988682›Full record

ArticleFrontiers in public health2025

Impact of China's National Volume-Based Procurement policy exclusively for insulin on the volume, expenditure and price: an interrupted time series analysis in Guangdong Province.

Changsong Jiang, Manling Nie, Yun Lu, Ting Jiang, Dan Guo, Peng Qi, Na Li, Feng Chang

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Changsong JiangSchool of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, China.
Manling NieHEOA Group, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Yun LuSchool of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, China.
Ting JiangNational Institute of Healthcare Security, Capital Medical University, Beijing, China.
Dan GuoNational Institute of Healthcare Security, Capital Medical University, Beijing, China.
Peng QiNational Institute of Healthcare Security, Capital Medical University, Beijing, China.
Na LiNational Institute of Healthcare Security, Capital Medical University, Beijing, China.
Feng ChangSchool of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to evaluate the effect of China's National Volume-Based Procurement (NVBP) policy exclusively for insulin by analyzing the trend in volume, expenditure, and price before and after NVBP policy. Methods: Taking Guangdong Province, China as an example, descriptive statistics and interrupted time series analysis were used to quantitatively measure the immediate and long-term effect of the NVBP policy on insulin volume, expenditure and price. In terms of volume, subgroup analysis is further conducted based on different generations and enterprise ownership to examine the impact of NVBP on the insulin utilization pattern. Results: Following the implementation of the NVBP policy, monthly insulin procurement volume increased significantly from 7.69 million to 9.37 million defined daily doses (DDDs), while monthly expenditure decreased from CNY 86.64 million to CNY 52.55 million, accompanied by a reduction in defined daily dose cost (DDDc) from CNY 11.24 to CNY 5.57. Interrupted time series analysis (ITSA) confirmed these trends, showing an immediate post-intervention increase of 1.547 million DDDs ( Conclusion: These findings demonstrate that the NVBP policy significantly reduced insulin expenditure while improving treatment accessibility and affordability for insulin. The policy effectively promoted therapeutic upgrading from human insulin to insulin analogue and optimized medication regimen. Notably, it stimulated domestic insulin market development through substitution effect. This multi-dimensional improvement exemplifies the principles of value-based healthcare delivery.

Indexed as

Drug CostsHealth ExpendituresHealth PolicyHypoglycemic AgentsInsulinChinaHumansInterrupted Time Series AnalysisHypoglycemic AgentsInsulinavailabilityinsulininterrupted time series analysisNational Volume-Based Procurementutilization patternvalue-based medicine

Identifiers

PMID40988682
PMCPMC12450972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.