Evidence map›Paper›PMID 40988646›Full record

ArticleJournal of clinical and experimental neuropsychology

Time in remission from depression predicts cognitive-affective regulation dynamics in everyday life.

Umiemah Farrukh, Sarah L Zapetis, Janet Li, Ellie P Xu, Jonathan P Stange

Abstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Umiemah FarrukhDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Sarah L ZapetisDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Janet LiDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Ellie P XuDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.
Jonathan P StangeDepartment of Psychology, University of Southern California, Los Angeles, CA, USA.

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Strengthening Stakeholder Engagement in Human Research Protections.UL1TR002003 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI KARNIK, NIRANJAN SUBHASH, MERMELSTEIN, ROBIN J. · 2016 to 2024
$33.7M
Ambulatory phenotyping with real-time indices of discordant affect regulation: Exploring opportunities for targeted intervention in depressionR01MH133842 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jonathan P Stange · 2023 to 2026
$3.0M
From Networks to the Real World: Integrating Neural and Autonomic Processes of LossK23MH112769 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI STANGE, JONATHAN P · 2017 to 2021
$931k
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NCATS NIH HHS UL1 TR002003NIMH NIH HHS K23 MH112769NIMH NIH HHS R01 MH133842
6 · The paper itself

Abstract

introductionImpairment in affect regulation continues even after remission from depression. However, little is known about whether difficulties in affect regulation persist or improve as time in remission grows and how they manifest in everyday life. With the aim of addressing this gap, we hypothesized that greater time in remission would correspond with more positive affect and perceived regulatory success, and with less negative affect, perseverative cognition, and momentary impulsivity. An exploratory aim was to determine whether executive dysfunction would mediate relationships between time in remission and regulatory outcomes.

methodA sample of 42 young adults with remitted major depressive disorder completed ecological momentary assessments, which included measures of positive and negative affect, perseverative cognition (rumination and worry), perceived regulatory success, and momentary impulsivity multiple times per day across the assessment period. Each person's mean level and variability of these constructs was computed and time in remission was calculated using a semi-structured clinical interview.

resultsRegression analyses indicated that a shorter time in remission predicted higher levels of negative affect, perseverative cognition, and momentary impulsivity and less perceived success with regulating affect in everyday life ( DISCUSSION: Although cognitive-affective processes often are conceptualized as traits, our data indicate that these measures are dynamic, fluctuating across the course of a week. Several of these processes also appear to attenuate and stabilize as depressive episodes become more distal. These findings have important clinical implications, suggesting that remitted individuals may continue to benefit from interventions to reduce impulsive and perseverative cognitive-behavioral patterns and improve regulation success and affective stability. Interventions may have particular utility earlier in remission when these skills may be more impaired, with the goal of restoring functioning and reducing the likelihood of relapse.

Indexed as

AffectEmotional RegulationExecutive FunctionImpulsive BehaviorMajor Depressive DisorderAdolescentAdultEcological Momentary AssessmentFemaleHumansMaleRemission InductionTime FactorsYoung Adultambulatory assessmentDepressionemotion regulationimpulsivityrumination

Identifiers

PMID40988646
PMCPMC12581654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.