Evidence map›Paper›PMID 40988512›Full record

ArticleBirth (Berkeley, Calif.)2026

Viability of Successful Vaginal Delivery in Triplet Pregnancies: A Retrospective Cohort Study Over 20 Years.

Petra M van Baar, Merle R van Dijk, Lidewij van de Mheen, Marjon A de Boer, Eva Pajkrt, Joost Velzel

Abstract read
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Article in Birth (Berkeley, Calif.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Petra M van BaarDepartment of Obstetrics and Gynecology, Amsterdam UMC, VU University, Amsterdam, the Netherlands.ORCID 0000-0001-6569-6529
Merle R van DijkDepartment of Obstetrics and Gynecology, OLVG Hospital, Amsterdam, the Netherlands.ORCID 0009-0009-7319-7506
Lidewij van de MheenGynaecologie Amsterdam, Amsterdam, the Netherlands.
Marjon A de BoerDepartment of Obstetrics and Gynecology, Amsterdam UMC, VU University, Amsterdam, the Netherlands.
Eva PajkrtAmsterdam Reproduction and Development Research Institute, Amsterdam UMC, Amsterdam, the Netherlands.
Joost VelzelDepartment of Obstetrics and Gynecology, Northwest Clinics, Alkmaar, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTriplet pregnancies are increasingly leaning toward planned cesarean deliveries (CD), yet data on determining factors and outcomes remain limited.

objectiveTo assess the success of vaginal delivery (VD) in triplet pregnancies and compare neonatal and maternal outcomes with those of CD.

methodsA retrospective cohort study included triplet pregnancies from 26 weeks' gestation onward in a tertiary center between 2000 and 2020. The primary outcome was the actual mode of delivery (successful VD, planned CD, or unplanned CD). Secondary outcomes included indications for CD, as well as neonatal and maternal outcomes.

resultsSeventy-one women were included. Of these, 41% attempted VD, with 90% successfully delivering vaginally. Planned CD was chosen by 59%, mainly for fetal (64%) or maternal (19%) indications, or patient preference (17%). Neonatal mortality did not differ significantly between planned VD and CD (aOR: 0.29; 95% CI: 0.06-1.50; p = 0.14). However, neonates born via VD compared to CD had lower risks for sepsis (aOR: 0.19; 95% CI: 0.04-0.94; p = 0.04) and retinopathy of prematurity (aOR: 0.17; 95% CI: 0.03-0.93; p = 0.04). Neonates born after VD had higher risks of infant respiratory distress syndrome (OR: 2.70; 95% CI: 1.03-7.08; p = 0.04) and interventricular hemorrhage (OR: 4.00; 95% CI: 1.20-13.35; p = 0.02), though these associations were not significant after adjusting for gestational age (p = 0.92 and p = 0.32, respectively).

conclusionsWomen opting for VD in triplet pregnancies had a 90% success rate. VD can be safe after careful case selection and access to highly trained personnel at a tertiary center. Centralization might enhance safety and outcomes, offering essential insights for clinicians.

Indexed as

Delivery, ObstetricPregnancy, TripletAdultCesarean SectionFemaleHumansInfant MortalityInfant, NewbornPregnancyPregnancy OutcomeRetrospective Studiescesarean deliverymaternal outcomemode of deliveryneonatal outcometripletsvaginal deliveryviability

Identifiers

PMID40988512
PMCPMC13156661

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.