ArticleImmunity, inflammation and disease2025
Low Thoracic Muscle Mass: A Novel Indicator of Poor Prognosis in Patients With Severe Fever With Thrombocytopenia Syndrome.
Article in Immunity, inflammation and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Commentary on "Low Thoracic Muscle Mass: A Novel Indicator of Poor Prognosis in Patients With Severe Fever With Thrombocytopenia Syndrome".Immunity, inflammation and disease · 2026Article
- Low Thoracic Muscle Mass: A Novel Indicator of Poor Prognosis in Patients With Severe Fever With Thrombocytopenia Syndrome.Immunity, inflammation and disease · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundSevere fever with thrombocytopenia syndrome (SFTS) poses a serious threat to public health due to its high mortality. Low thoracic muscle mass predicts poor clinical outcomes in many diseases, but its significance in SFTS remains unclear.
methodsThis retrospective study involved 210 SFTS patients admitted to the First Affiliated Hospital of Anhui Medical University from 2020 to 2023. All subjects underwent chest computed tomography (CT) examination. Skeletal muscle index (SMI) was measured by CT images at the level of the twelfth thoracic vertebra (T12). The clinical data of patients from the survival and non-survival groups were compared, and the prognostic value of T12-SMI in SFTS patients was evaluated through least absolute shrinkage and selection operator regression and univariate and multivariate Cox regression.
resultsPatients in the non-survival group had a lower SMI. Receiver operating characteristic analysis indicated that SMI may predict adverse outcomes in patients with SFTS. Multivariate Cox regression analysis demonstrated that SMI was independently connected to negative outcomes of SFTS. T12-SMI was correlated with albumin and creatinine.
conclusionLow SMI is associated with adverse outcomes in patients with SFTS. SMI may serve as a reliable prognostic marker for SFTS in clinical settings.
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