Evidence map›Paper›PMID 40988445›Full record

Observational studyAnnals of medicine2025

Preoperative anxiety state is an independent risk factor for delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: a single-center retrospective case-control study.

Zhengwang Wang, Yuan Chen, Xinyu Ge, Ke Zhang, Jie Zhu, Peng Wang, Peng Xu, Jie Yao

Abstract readObservational Study
In one paragraph

Observational study in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Zhengwang WangDepartment of Hepatobiliary and Pancreatic Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Jiangsu Province, China.ORCID 0000-0002-1070-6168
Yuan ChenDepartment of Hepatobiliary and Pancreatic Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Jiangsu Province, China.
Xinyu GeDepartment of Hepatobiliary and Pancreatic Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Jiangsu Province, China.
Ke ZhangDepartment of Hepatobiliary and Pancreatic Surgery, The Yangzhou School of Clinical Medicine of Dalian Medical University, Jiangsu Province, China.
Jie ZhuDepartment of Hepatobiliary and Pancreatic Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Jiangsu Province, China.
Peng WangDepartment of Hepatobiliary and Pancreatic Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Jiangsu Province, China.
Peng XuDepartment of Hepatobiliary and Pancreatic Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Jiangsu Province, China.
Jie YaoDepartment of Hepatobiliary and Pancreatic Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Jiangsu Province, China.ORCID 0000-0001-5447-893X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelayed gastric emptying (DGE) is one of the prevalent complications following pylorus-preserving pancreaticoduodenectomy (PPPD). Anxiety is one of the common psychological comorbidities among tumor patients. However, its influence on the development of DGE post-PPPD remains elusive. Thus, this study aimed to explore the relationship between anxiety states and the incidence of DGE after PPPD.

methodsThis single-center, retrospective case-control study enrolled 150 patients who underwent PPPD between January 2020 and December 2022. Preoperative anxiety state was assessed using the Hamilton Anxiety Scale (HAMA), and patients were stratified into two groups based on the presence or absence of DGE. Lastly, risk factors for DGE were analyzed based on clinical data, laboratory indicators, postoperative complications, and other indicators.

resultsThe incidence of postoperative DGE was 28.67%. Patients who developed DGE had significantly higher body mass index (BMI) (23.50 ± 3.85 vs 22.20 ± 2.39,

conclusionAnxiety state, BMI, hypertension, preoperative blood lipid levels, and albumin level on the third day after surgery were related to the occurrence of DGE after PPPD. Among them, anxiety state was identified as an independent risk factor for DGE. These findings highlight the need for implementing timely and appropriate psychological interventions in patients undergoing PPPD to minimize the risk of postoperative DGE.

trial registrationClinicalTrials.gov Identifier: ChiCTR2400090370.

Indexed as

AnxietyGastroparesisPancreaticoduodenectomyPostoperative ComplicationsAgedBody Mass IndexCase-Control StudiesFemaleGastric EmptyingHumansIncidenceMaleMiddle AgedPreoperative PeriodPylorusRetrospective Studiesanxiety statedelayed gastric emptyingPylorus-preserving pancreaticoduodenectomyrisk factor analysis

Identifiers

PMID40988445
PMCPMC12462420

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.