SynthesisCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025
Direct Comparison of Urgent Transcatheter Aortic Valve Implantation and Balloon Aortic Valvuloplasty: A Systematic Review and Meta-Analysis.
Synthesis in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- When Time Matters in Aortic Stenosis: Can Transcatheter Aortic Valve Replacement Make a Difference in Non-Elective Cases?Reviews in cardiovascular medicine · 2026Pooled it
- Transcatheter management of cardiogenic shock in severe aortic stenosis.Frontiers in cardiovascular medicine · 2026Review
- Aortic stenosis and sleep disordered breathing: The effects of interventional management.Science progressReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectiveAortic stenosis (AS) may complicate cardiogenic shock (CS) or acute decompensated heart failure (ADHF) in a small but significant number of patients. In such cases, urgent treatment is necessary to prevent mortality and adverse outcomes. Transcatheter aortic valve implantation (TAVI) and balloon aortic valvuloplasty (BAV) represent the main treatment options, however, limited studies have compared them directly. Therefore, this systematic review and meta-analysis aims to synthesize available studies directly comparing urgent TAVI and BAV, in respect to reported outcomes.
methodsWe systematically searched MEDLINE/PubMed, Scopus and Web of Science for studies comparing outcomes in patients with CS or ADHF undergoing urgent TAVI or BAV. Followingly, a meta-analysis of all included studies was performed.
resultsA total of six studies, including 21,020 patients (10,597 patients undergoing TAVI and 10,423 patients undergoing BAV) were analyzed. Regarding in-hospital mortality, it was found to be significantly lower in patients undergoing urgent TAVI, compared to BAV (risk ratio [RR]: 0.53; 95% confidence interval (CI): 0.32-0.87]. Moreover, urgent TAVI was also associated with significantly lower all-cause mortality at 30-days follow up (RR 0.51, 95% CI: 0.31-0.84).
conclusionIn this meta-analysis of observational, retrospective studies including patients undergoing urgent transcatheter interventions for acute AS, TAVI is associated with significantly reduced in-hospital and 30-days mortality, in comparison to BAV. More larger studies, reporting extended follow-up and adverse events' rates, are needed to safely conclude regarding the benefit of urgent interventions in the acute care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.