Evidence map›Paper›PMID 40988245›Full record

Observational studyMedicine2025

Negative affect in fibromyalgia in comparison to controls: A cross-sectional investigation of risk and protective factors.

Maurício Sygel, Carlos Eduardo Consentino Machado, Guilherme Welter Wendt

Abstract readObservational Study
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maurício SygelHealth Sciences Center, Western Paraná State University, Postgraduate Program in Applied Health Sciences, Francisco Beltrão, Brazil.
Carlos Eduardo Consentino MachadoHealth Sciences Center, Western Paraná State University, Postgraduate Program in Applied Health Sciences, Francisco Beltrão, Brazil.
Guilherme Welter WendtHealth Sciences Center, Western Paraná State University, Postgraduate Program in Applied Health Sciences, Francisco Beltrão, Brazil.ORCID 0000-0002-9014-6200

Funding

Superintendência Geral de Ciência, Tecnologia e Ensino Superior (SETI)
6 · The paper itself

Abstract

As a complex biopsychosocial dysregulation, fibromyalgia poses a significant challenge for healthcare personnel in addition to the unique burden on patients. Past studies have explored the role of negative affect in a myriad of chronic conditions with the intent of providing valuable data to reshape current treatment measures. This study seeks to analyze the factors associated with clinically significant self-reported levels of negative affect in people with and without fibromyalgia. Using a cross-sectional design, individuals aged 18 years or older, with and without fibromyalgia, participated in the research. A logistic model indicated 2 risk factors, and 1 protective factor associated with clinically significant levels of negative affect, namely age (those over 50 years had a reduced risk for negative affect by approximately 63%), whereas the presence of comorbidities and having fibromyalgia increased the risk by 326% and 388%, respectively. The results add to explanatory models that might be useful in understanding the interdependence between the experience of long-lasting pain and the links with negative affect.

Indexed as

AffectFibromyalgiaAdultAgedAge FactorsCase-Control StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedProtective FactorsRisk Factorscomorbiditiesfibromyalgianegative affectrisk factors

Identifiers

PMID40988245
PMCPMC12459579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.