Evidence map›Paper›PMID 40988068›Full record

ArticleMicrobial cell factories2025

Characterizing the growth of PHA-producing microorganisms on short-chain carboxylic acids.

Steven Leonhardt, Pravesh Tamang, Günter E M Tovar, Susanne Zibek

Abstract read
In one paragraph

Article in Microbial cell factories, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pressure Dependent Changes in COBiotechnology journal · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Steven LeonhardtFraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany.
Pravesh TamangFraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany.
Günter E M TovarFraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany.
Susanne ZibekFraunhofer Institute for Interfacial Engineering and Biotechnology IGB, Stuttgart, Germany. susanne.zibek@igb.fraunhofer.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Short-chain carboxylic acids are important chemical intermediates in anaerobic treatment or thermal hydrolysis of biowaste. They are a crucial precursor for the production of Polyhydroxyalkanoate (PHA) by various microorganisms. However, there is limited data on the growth behavior of PHA-producing microorganisms on carboxylic acids and their tolerance range. Therefore, this study aims to systematically determine the growth behavior of four commonly used PHA-producing microorganisms (Cupriacidus necator, Pseudomonas putida, Azohydromonas australica, and Haloferax mediterranei) on different carboxylic acids (formic, acetic, propionic, valeric, and levulinic acid). Batch experiments were conducted in a microbioreactor to determine the maximum specific growth rates (µ

Indexed as

BacteriaCarboxylic AcidsPolyhydroxyalkanoatesBioreactorsFormatesLevulinic AcidsPseudomonas putidaCarboxylic AcidsFormatesformic acidlevulinic acidLevulinic AcidsPolyhydroxyalkanoatesAnd Haloferax mediterranei DSM 1411Azohydromonas australica DSM 1124Carboxylic acidsCupriacidus necator H16InhibitionPolyhydroxyalkanoatePseudomonas Putida KT2440Specific growth rate

Identifiers

PMID40988068
PMCPMC12455835

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.