Evidence map›Paper›PMID 40988033›Full record

ReviewBMC ophthalmology2025

Waiting is worthwhile: ROP stage 5 with stage regression due to retinal reattachment after scleral buckling surgery (encircling band) - a case report with review of the literature.

A Khamees, V Schöneberger, S Kaya, T Guthoff, G Geerling, R Guthoff

Abstract readCase ReportsReview
In one paragraph

Review in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A KhameesDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Düsseldorf, Germany.
V SchönebergerDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Düsseldorf, Germany.
S KayaDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Düsseldorf, Germany.
T GuthoffDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Düsseldorf, Germany.
G GeerlingDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Düsseldorf, Germany.
R GuthoffDepartment of Ophthalmology, Heinrich-Heine University Düsseldorf, Universitätsaugenklinik Düsseldorf, Düsseldorf, Germany. rainer.guthoff@med.uni-duesseldorf.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetinopathy of Prematurity (ROP) can progress despite standard treatments such as laser coagulation and VEGF inhibitors. Scleral buckle surgery (SBS) is a surgical option in stage 4 ROP, though anatomical success in stage 5 is rare. We present a unique case of spontaneous retinal reattachment after SBS in stage 5 ROP without further intervention. CASE PRESENTATION: A female infant, born at 24 + 2 weeks and weighing 440 g, developed stage III ROP with plus disease in the left eye. Despite laser treatment, the disease progressed to stage 4B, prompting SBS at 39 weeks PMA. Within three weeks, the eye advanced to stage 5 ROP. Surprisingly, complete retinal re-attachment occurred spontaneously within four months. Although the anatomical outcome was favorable, the left eye developed high myopia and amblyopia.

conclusionsThis case highlights the potential for spontaneous improvement after SBS in advanced ROP. While anatomical success is possible, functional outcomes may remain poor. Individualized follow-up and further research on subretinal fluid dynamics are needed to optimize treatment strategies.

Indexed as

Retinal DetachmentRetinopathy of PrematurityScleral BucklingFemaleHumansInfant, NewbornRemission, SpontaneousVisual AcuityPersistent subretinal fluidRetinal detachmentRetinopathy of prematurity (ROP)Scleral buckle surgery

Identifiers

PMID40988033
PMCPMC12455843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.