Evidence map›Paper›PMID 40987993›Full record

ArticleCancer causes & control : CCC2025

A survey of cancer affiliate network hubs in the US: goals, composition, resources, and evaluation.

Madison M Wahlen, Mary C Schroeder, Pamela Y Bojorquez, Sarah A Birken, Jason T Semprini, Jessica S Gorzelitz, Aaron T Seaman, Leila Sadri, Kristy Broman, Ingrid M Lizarraga and 1 more

Abstract read
In one paragraph

Article in Cancer causes & control : CCC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Madison M WahlenDepartment of Epidemiology, University of Iowa College of Public Health, Iowa City, USA.
Mary C SchroederDivision of Health Services Research, University of Iowa College of Pharmacy, 180 South Grand Avenue, 346 CPB, Iowa City, IA, 52242, USA. mary-schroeder@uiowa.edu.
Pamela Y BojorquezCollege of Arts and Sciences, Loyola University Chicago, Chicago, USA.
Sarah A BirkenDepartment of Implementation Science, Wake Forest University School of Medicine, Winston-Salem, USA.
Jason T SempriniDepartment of Public Health, Des Moines University College of Health Sciences, West Des Moines, USA.
Jessica S GorzelitzDepartment of Health and Human Physiology, University of Iowa College of Liberal Arts and Sciences, Iowa City, USA.
Aaron T SeamanDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, USA.
Leila SadriO'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, USA.
Kristy BromanDepartment of Surgery, University of Alabama at Birmingham, Birmingham, USA.
Ingrid M LizarragaDepartment of Surgery, University of Iowa Hospitals and Clinics, Iowa City, USA.
Mary E CharltonDepartment of Epidemiology, University of Iowa College of Public Health, Iowa City, USA.

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Jon C.D. Houtman · 2000 to 2026
$70.0M
Effectiveness and implementation of a health system intervention to improve quality of cancer care for rural, underserved patientsR01CA254628 · NCI · UNIVERSITY OF IOWA · PI CHARLTON, MARY E. · 2021 to 2025
$3.6M
NCI NIH HHS P30 CA086862NCI NIH HHS R01 CA254628NCI NIH HHS R01CA254628
6 · The paper itself

Abstract

purposeCommunity hospitals play a critical role in cancer care delivery across the US but face challenges in providing needed services and specialized expertise. Cancer affiliate networks, i.e., formal/informal relationships between a large cancer center (hub) and community cancer centers (affiliates), can potentially improve quality in small hospitals where many Americans receive care. However, published descriptions of these networks are lacking. Thus, we aimed to identify and describe cancer networks across the US.

methodsWe assembled a listing of US-based cancer affiliate networks using a formal web searching strategy and surveyed hub representatives regarding network goals, composition, services/resources, and methods for evaluating success.

resultsSixteen of 21 identified networks responded to the survey. All networks focused on improving access/delivery of high-quality cancer care at affiliate sites with common goals that included improving access to services, supporting quality improvement, and recruitment for clinical trials. Networks often included multiple healthcare systems; few had financial ownership over affiliates; and most had participation requirements (e.g., accreditation). Hubs extended a variety of specialized services/resources to affiliates (e.g., clinical trials, genetic counseling, virtual tumor boards). Approaches to evaluation and quality improvement varied.

conclusionWe found that cancer affiliate networks generally aimed to improve access and delivery of high-quality cancer care, with considerable variation in the activities used to achieve and evaluate progress toward these goals. As networks continue to operate and emerge, research is needed to identify best practices for optimizing networks' influence on the quality of care in resource-constrained hospitals and enabling effective scaling of the cancer affiliate network model.

Indexed as

Cancer Care FacilitiesCommunity NetworksNeoplasmsDelivery of Health CareHumansUnited StatesCancer care qualityCancer networksSurveys and questionnaires

Identifiers

PMID40987993
PMCPMC12630224

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.