Evidence map›Paper›PMID 40987863›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

An overview on manifestation and management of glossopharyngeal schwannoma: a systematic review.

Francesco Chiari, Pierre Guarino, Matteo Fermi, Claudio Donadio Caporale, Livio Presutti, Gabriele Molteni

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francesco ChiariOtolaryngology Head and Neck Unit, "Santo Spirito" Hospital, Pescara, Italy.
Pierre GuarinoOtolaryngology Head and Neck Unit, "Santo Spirito" Hospital, Pescara, Italy. pierreguarino@hotmail.com.ORCID http://orcid.org/0000-0003-3796-9483
Matteo FermiOtolaryngology and Audiology Unit, IRCCS Azienda Ospedaliero Universitaria of Bologna, Bologna, Italy.
Claudio Donadio CaporaleOtolaryngology Head and Neck Unit, "Santo Spirito" Hospital, Pescara, Italy.
Livio PresuttiOtolaryngology and Audiology Unit, IRCCS Azienda Ospedaliero Universitaria of Bologna, Bologna, Italy.
Gabriele MolteniOtolaryngology and Audiology Unit, IRCCS Azienda Ospedaliero Universitaria of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesGlossopharyngeal schwannoma is a rare benign tumor of myelin-producing Schwann cells. Kaye and Pellet classified lower cranial nerves' (CN) schwannomas into 4 different categories, according to size, location, and tumoral extension. This systematic review aims to provide a comprehensive overview of epidemiology, clinical manifestation, diagnostic features, therapeutic management, and outcomes of patients affected by IX CN schwannoma.

methodsA systematic literature review has been performed following the PRISMA 2020 checklist statement. A computerized search has been carried on by an extensive set of queries on the Embase/PubMed, Scopus, and Web of Sciences databases, relating to papers published from 1975 to 2024.

resultsOf the 77 patients affected by glossopharyngeal schwannoma reviewed in 37 studies, 52% were females and 48% were males. The mean age of patients was 41 years. Most of the reported lesions were intra-cranial type A tumors (69%), according to the high prevalence of ear disturbances (77%) and cerebellar signs (23%). The full removal of the tumor was described in 96% of cases with only 4 cases of tumoral recurrences.

conclusionCurrent evidence suggests overall favorable oncological outcomes and a low rate of recurrence. Surgery is considered the gold standard treatment for glossopharyngeal schwannomas and it is generally indicated when the tumor causes significant neurological symptoms, mass effect, or progressive growth. Nonetheless, radiosurgery is not commonly used.

Indexed as

Cranial Nerve NeoplasmsGlossopharyngeal Nerve DiseasesNeurilemmomaHumansGlossopharyngeal nerveNeurinomaNeuromaSchwannoma

Identifiers

PMID40987863

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.