Evidence map›Paper›PMID 40987859›Full record

Observational studyEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Impact of body mass index on chronic rhinosinusitis: disease burden and treatment outcomes.

Kannanunni S, Meera N Khadilkar, Thripthi Rai

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kannanunni SDepartment of Otorhinolaryngology - Head and Neck, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.ORCID http://orcid.org/0009-0009-8563-9762
Meera N KhadilkarDepartment of Otorhinolaryngology - Head and Neck, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.ORCID http://orcid.org/0000-0002-2006-8913
Thripthi RaiDepartment of Otorhinolaryngology - Head and Neck, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India. tripthi.rai@manipal.edu.ORCID http://orcid.org/0000-0002-9374-4628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic rhinosinusitis (CRS) is a prevalent inflammatory condition that significantly affects quality of life, with obesity emerging as a key modifiable risk factor. Both body mass index (BMI) and waist circumference (WC) are associated with increased CRS prevalence, severity, and potentially poorer treatment outcomes due to sustained inflammation and altered immune responses. This study investigates how BMI and WC influence CRS severity and response to therapy.

methodsThis two-year observational study included adult CRS patients, assessing BMI, WC, Rhinosinusitis Disability Index (RSDI), Sinonasal Outcome Test-22 (SNOT-22), and Lund-Kennedy endoscopic scores, before and after standard medical/ surgical treatment (3 months).

resultsOf the 43 CRS patients, most showed significant symptoms and endoscopic score improvements over three months, regardless of BMI or waist circumference. While RSDI and Lund-Kennedy scores showed some group-wise differences, overall outcomes were not significantly influenced by BMI or WC categories.

conclusionObesity measures, as indicated by BMI, do not influence baseline CRS symptom severity but are associated with greater endoscopic improvement following treatment. All BMI groups demonstrate significant symptom relief, underscoring the effectiveness of therapy across varying body weight categories.

Indexed as

Body Mass IndexObesityRhinitisSinusitisAdultAgedChronic DiseaseCost of IllnessEndoscopyFemaleHumansMaleMiddle AgedQuality of LifeRhinosinusitisSeverity of Illness IndexBody mass indexNasal polypsObesityRhinosinusitisWaist circumference

Identifiers

PMID40987859
PMCPMC12605512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.