ArticleBritish journal of anaesthesia2025
Peripheral nerve blocks for perioperative analgesia: das Kind mit dem Bade ausschütten...throwing the baby out with the bathwater?
Article in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block: a Single-blinded Randomised Controlled Trial
Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block: a Single-blinded Randomised Controlled Trial
Who cites it
2 citing papers in PubMed.
- Article
- Intercostal nerve blocks take the lead: rethinking regional analgesia for video-assisted thoracic surgery.Journal of thoracic disease · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are many benefits of using peripheral nerve blocks (PNBs) for perioperative anaesthesia and analgesia; however, one of their major drawbacks is rebound pain upon resolution of the block. In examining a database of approximately 23 000 patients who received PNB along with general anaesthesia for orthopaedic surgery, Chung and colleagues found that PNB administration before incision was associated with lower maximum pain scores and lower opioid use in the postanaestheisa care unit, but was also associated with higher maximum pain scores, a 23% increase in opioid consumption during the hospital stay, and an increase in opioid prescriptions at 30 days after discharge. They also found that the use of single-shot PNBs was associated with decreased chronic pain diagnoses 1 year after surgery. Some of the discordant findings in this study might be attributed to its retrospective nature and the use of databases to examine this issue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.