Evidence map›Paper›PMID 40987611›Full record

ArticleJournal of natural products2025

Discovery of Isonitrile Lipopeptide Chalkophores from Pathogenic Mycobacteria.

Kaimin Jia, Helen Sun, Quang Kim Huynh, Dunya Al Marzooqi, Yongle Du, Yiyan Zhou, Wenjun Zhang

Abstract read
In one paragraph

Article in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaimin JiaDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California 94720, United States.ORCID 0000-0002-5947-5735
Helen SunDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California 94720, United States.
Quang Kim HuynhDepartment of Chemistry, University of California Berkeley, Berkeley, California 94720, United States.
Dunya Al MarzooqiDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California 94720, United States.
Yongle DuDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California 94720, United States.ORCID 0000-0002-5727-3355
Yiyan ZhouDepartment of Molecular and Cell Biology, University of California Berkeley, Berkeley, California 94720, United States.
Wenjun ZhangDepartment of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California 94720, United States.ORCID 0000-0001-9348-972X

Funding

Biosynthesis of unusual bio-orthogonal functionalities in natural productsR01GM136758 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ZHANG, WENJUN · 2020 to 2023
$1.5M
Biosynthesis of Unusual Bio-Orthogonal Functionalities in Natural ProductsR35GM153289 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Wenjun Zhang · 2024 to 2026
$1.1M
Acquisition of a Cryoprobe and Related Accessories for a 600 MHz NMR Spectrometer to Support Health Research Activities at the University of California, BerkeleyS10OD024998 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI HARTWIG, JOHN F · 2018 to 2018
$265k
NIGMS NIH HHS R01 GM136758NIGMS NIH HHS R35 GM153289NIH HHS S10 OD024998
6 · The paper itself

Abstract

The virulence-associated isonitrile lipopeptide (INLP) biosynthetic gene cluster is conserved across

Indexed as

LipopeptidesNitrilesNontuberculous MycobacteriaCopperMethyltransferasesMolecular StructureMultigene FamilyMycobacterium tuberculosisCopperLipopeptidesMethyltransferasesNitriles

Identifiers

PMID40987611
PMCPMC12462896

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.