Evidence map›Paper›PMID 40987482›Full record

ArticleRenal failure2025

Protective effects of ischemic pre-conditioning and boldine on unilateral renal ischemia reperfusion injury-induced brain damage: apoptotic, pyroptotic, inflammatory, and oxidative pathways.

Esra Tekin, Gülay Kip, Ayşegül Küçük, Zeynep Yığman, Mustafa Kavutçu, Mustafa Arslan

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Esra TekinDepartment of Physiology, Faculty of Medicine, Kutahya Health Sciences University, Kutahya, Turkey.ORCID 0000-0002-9684-3277
Gülay KipDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID 0000-0001-5242-5332
Ayşegül KüçükDepartment of Physiology, Faculty of Medicine, Kutahya Health Sciences University, Kutahya, Turkey.ORCID 0000-0001-9316-9574
Zeynep YığmanDepartment of Histology and Embryology, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID 0000-0003-1985-9280
Mustafa KavutçuDepartment of Medical Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID 0000-0002-5135-8067
Mustafa ArslanDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Gazi University, Ankara, Turkey.ORCID 0000-0003-4882-5063

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the effects of ischemic pre-conditioning and boldine on unilateral renal ischemia-reperfusion (IR) injury-induced brain damage. Thirty rats were divided into five groups (

Indexed as

AporphinesIschemic PreconditioningKidneyReperfusion InjuryAnimalsApoptosisBrainDisease Models, AnimalInflammationMaleOxidative StressPyroptosisRatsAporphinesboldineapoptosisboldinebrainpre-conditioningpyroptosisRenal ischemia reperfusion injury

Identifiers

PMID40987482
PMCPMC12459197

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.