ArticleJournal of clinical periodontology2026
The Association of Periodontitis With Risk of Prevalent and Incident Metabolic Syndrome.
Article in Journal of clinical periodontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Association Between Glyco-Lipid Seven-Factor Index, a Novel Composite Glyco-Lipid Index, and Periodontitis: A Cross-Sectional Study.International dental journal · 2026Article
- Metabolic Syndrome and Periodontitis-From Shared Mechanisms to Interdisciplinary Care: A Narrative Review of Clinical Evidence.Journal of clinical medicine · 2026Review
- Dental disease among adults with and without HIV in the MACS/WIHS Combined Cohort Study (MWCCS).BMC oral health · 2026Article
- The Association of Periodontitis With Risk of Prevalent and Incident Metabolic Syndrome.Journal of clinical periodontology · 2026Article
- A Comparison of Periodontal Health in Elderly Individuals with and Without Metabolic Syndrome: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
aimTo investigate whether periodontitis is associated with prevalent and incident metabolic syndrome (MetS). MATERIALS AND
methodsThe baseline study included 4183 individuals from a population-based survey (DILGOM) in 2007 and follow-up of 1047 participants with clinical re-examination in 2014. The risk of periodontitis was assessed with saliva biomarkers using a validated, three-group cumulative risk score for periodontitis (CRS I, II and III).
resultsIn fully adjusted models, CRS III was associated with prevalent MetS (OR: 1.35, 95% CI [1.11-1.65]), high waist circumference (1.55 95% CI [1.26-1.91]), high blood pressure (1.29 95% CI [1.05-1.59]) and the number of MetS components (β: 0.18, 95% CI [0.06-0.30]). Among participants without MetS at baseline (n = 618), 128 (20.7%) developed MetS during follow-up. In the fully adjusted model, CRS III trended positively with incident MetS (RR: 1.55, 95% CI [ 0.96-2.51]) in the whole population and had a significant positive association in women (2.06, 95% CI [1.08-3.94]), and in non-smokers (1.78, 95% CI [1.01-3.14]). The risk between CRS and incident MetS was mediated via systemic inflammation.
conclusionPeriodontitis is associated with an increased risk of having metabolic syndrome and, in particular, clearly with the number of MetS components: abdominal obesity, hyperglycaemia and hypertension. Systemic inflammation may elucidate the observed higher risk of incident MetS.
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