ArticleJBRA assisted reproduction2025
Impact of embryo storage time after vitrification on pregnancy and implantation rates.
Article in JBRA assisted reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effect of cryopreservation duration on pregnancy outcomes in embryos: a systematic review and meta-analysis.Human reproduction open · 2026Review
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe study aimed to assess whether the storage time after vitrification affects clinical pregnancy and implantation rates.
methodsThis multicentric retrospective study involved 1568 cycles of autologous frozen embryo transfers between 2015 and 2019. The patients were divided into groups based on storage time to assess its impact on pregnancy and implantation rates. The variables analyzed were maternal age, cryopreservation stage, and embryo transfer" stage. Logistic regression was used to investigate associations between storage duration, patient age, and transfer outcomes. The study was approved by the Research Ethics Committee of UFMG and informed written consent was waivered.
resultsThe length of embryo storage showed an inverse association with pregnancy and implantation rates, correlating with patient age and embryo stage at the time of transfer. Patients aged 36 to 40, and 41 years or older had lower rates of clinical pregnancy compared to those under 35 years of age. Additionally, vitrified embryos transferred at the cleavage stage demonstrated lower rates of clinical pregnancy and implantation compared to those at the blastocyst stage. These results suggest that storage duration, patient age, and embryo stage significantly influence frozen embryo transfer (FET) outcomes.
conclusionsStorage duration, patient age, and embryo stage can affect FET outcomes, with older women and embryos at the cleavage stage, possibly experiencing lower pregnancy and implantation rates after extended storage.
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