Evidence map›Paper›PMID 40986083›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2025

Retrospective evaluation of a funnel-shaped mesh for the prevention of parastomal hernias in patients with permanent end colostomy.

Francesco Brucchi, Maria Rennis, Pietro Achilli, Lorenzo Morini, Pietro Carnevali, Matteo Origi, Gianlorenzo Dionigi, Giovanni Ferrari

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Francesco BrucchiGeneral Surgery Residency Program, University of Milan, Milan, Italy. francesco.brucchi@unimi.it.ORCID 0000-0003-3191-4369
Maria RennisGeneral Surgery Residency Program, University of Milan, Milan, Italy.
Pietro AchilliDepartment of Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Lorenzo MoriniDepartment of Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Pietro CarnevaliDepartment of Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Matteo OrigiDepartment of Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Gianlorenzo DionigiDivision of Surgery, Istituto Auxologico Italiano, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.
Giovanni FerrariDepartment of Mini-Invasive Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParastomal hernia (PSH) is the most common long-term complication after abdominoperineal resection (APR) with permanent end colostomy. Although prophylactic mesh placement has been suggested to reduce the rate of PSH, the optimal mesh type and surgical technique remain unclear. Recently, three-dimensional funnel-shaped meshes have been introduced to stabilize the bowel loop and minimize stoma-related mechanical stress, potentially reducing the incidence of PSH.

methodsThis retrospective cohort study, reported in accordance with STROBE guidelines, included consecutive patients who underwent elective laparoscopic permanent end colostomy (PEC) between 2011 and 2019 at a single institution. Patients were assigned to either a group without mesh or a group that received prophylactic intraperitoneal funnel-shaped mesh. The primary endpoint was radiologically confirmed PSH incidence. Kaplan-Meier analysis and Cox regression were used to assess differences in cumulative PSH risk over time.

resultsSeventy-five patients were included (mesh group: 37; no-mesh group: 38), with a median follow-up of 46 and 43 months, respectively. The mesh group had a lower, but not statistically significant, absolute incidence of PSH (21.6% vs. 39.5%, p = 0.094). Importantly, the Kaplan-Meier analysis revealed a significantly lower cumulative incidence of PSH in the mesh group over time (p= 0.033). Postoperative complication rates were comparable between the groups. CONUSIONS: Prophylactic placement of a funnel-shaped mesh during PEC was associated with a reduced cumulative incidence of PSH over long-term followup without increasing surgical morbidity. These results underline the potential benefit of funnel-shaped meshes in PSH prevention and highlight the need for prospective randomized studies.

Indexed as

ColostomyHernia, VentralIncisional HerniaPostoperative ComplicationsSurgical MeshSurgical StomasAgedFemaleHumansIncidenceLaparoscopyMaleMiddle AgedRetrospective StudiesColorectal surgeryFunnel-shaped meshLong-term outcomesParastomal hernia preventionPermanent end colostomyProphylactic mesh placement

Identifiers

PMID40986083
PMCPMC12457522

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.