ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025
Crosslinking for post refractive surgery ectasia: application and clinical outcomes.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePost-laser vision correction ectasia (PLE) is one of the more serious complications that can happen after laser vision correction surgery, manifested as progressive thinning of the cornea and accompanied by increased myopia and irregular astigmatism. We present a case series of PLE managed with pachymetry-guided Epithelium-Off accelerated crosslinking (ACXL) using the M nomogram, in a long term-follow-up evaluation.
methodsBefore-after comparative case series of 13 eyes of 10 patients (3 bilateral treatments) diagnosed with PLE underwent standardized over-the-Flap crosslinking technique (S-ACXL) with epithelial removal (Epi-Off). UV-A irradiation was delivered with continuous and pulsed light mode of irradiation in a range of UV power between 9 and 30mW, customized according to baseline corneal pachymetry (M nomogram), maintaining the standardized fluence.
resultsNo statistically significant differences were found in sim-Kmax, mean pupillary power and Kavg, despite a general tendency to improvement. The stability of the corneal thickness during the entire follow-up in all treated patients confirmed the stabilization of PLE in association with statistically significant reduction (P 0.005) of the posterior elevation (PE). Corrected distance visual acuity showed a statistically significant improvement of + 2 ± 0.57 Snellen Lines (P = 0.05). Coma, high-order aberrations and Spherical aberrations decreased significantly (P 0.005) explaining the functional improvement. No adverse events were recorded.
conclusionsVisual acuities improved in all patients and the disease was stable over a long-term follow-up, confirming the usefulness of pachymetry-guided ACXL in blocking the progression of PLE at the same time of improving the functional outcomes.
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Registered trials
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