Evidence map›Paper›PMID 40986039›Full record

ArticleInternational orthopaedics2025

Impact of mechanical axis position and coronal plane alignment phenotypes on clinical outcomes in medial opening wedge high tibial osteotomy.

Ahmetcan Erdem, Vahdet Uçan, Gökhan Lebe, Muhammet Ali Geçkalan, Cemil Burak Demirkıran, Ali Toprak, Nurzat Elmalı

Abstract read
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmetcan ErdemDepartment of Orthopaedics and Traumatology, Bezmialem Foundation University Medical Faculty Hospital, Istanbul, Turkey.
Vahdet UçanDepartment of Orthopaedics and Traumatology, Bezmialem Foundation University Medical Faculty Hospital, Istanbul, Turkey.
Gökhan LebeDepartment of Orthopaedics and Traumatology, Bezmialem Foundation University Medical Faculty Hospital, Istanbul, Turkey.
Muhammet Ali GeçkalanDepartment of Orthopaedics and Traumatology, Bezmialem Foundation University Medical Faculty Hospital, Istanbul, Turkey.
Cemil Burak DemirkıranOrthopaedics and Traumatology, Republic of Turkey Ministry of Health Saray State Hospital,, Tekirdağ, Turkey.
Ali ToprakDepartment of Basic Medical Sciences, Division of Biostatistics and Medical Informatics,, Bezmialem Foundation University Medical Faculty Hospital, Istanbul, Turkey.
Nurzat ElmalıDepartment of Orthopaedics and Traumatology, Bezmialem Foundation University Medical Faculty Hospital, Istanbul, Turkey. nelmali@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn medial opening wedge high tibial osteotomy (MOWHTO), the goal extends beyond lateralizing the mechanical axis; restoring a horizontal joint line is crucial for optimal biomechanics. The Coronal Plane Alignment of the Knee (CPAK) classification, which incorporates mechanical axis deviation and joint line obliquity (JLO), offers a phenotype-based framework, though its application in MOWHTO remains underexplored. MATERIALS AND

methodsA retrospective review included 147 knees from 123 patients undergoing MOWHTO with at least 24 months of follow-up. Radiographic parameters assessed were mFTA, MPTA, mLDFA, JLCA, aHKA, and JLO. Knees were categorized based on postoperative weight-bearing line (WBL) positions, and CPAK phenotypes were recorded pre- and postoperatively. Clinical outcomes were evaluated using the Hospital for Special Surgery (HSS) knee score.

resultsPreoperatively, CPAK type I (varus, apex distal JLO) predominated (82.3%). Postoperatively, many transitioned to Types V (neutral, apex neutral JLO, 24.5%) and VI (valgus, apex neutral JLO, 17.7%), both yielding significantly higher HSS scores (p < 0.001). Optimal outcomes were observed with a WBL between 50% and 60%. The mean aHKA improved from - 7.35° to + 1.59°, while JLO corrected from 172.4° to 180.8°.

conclusionThis study demonstrates that transitions to CPAK Types V-VI, with 50-60% WBL and horizontal joint line restoration, are linked to improved HSS scores, highlighting the CPAK classification's potential for guiding individualized correction strategies in MOWHTO. LEVEL OF EVIDENCE: Level III (retrospective comparative study).

Indexed as

Knee JointOsteoarthritis, KneeOsteotomyTibiaAdultAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedPhenotypeRadiographyRetrospective StudiesTreatment OutcomeWeight-BearingClinical outcomesCoronal plane alignmentCPAK classificationHigh tibial osteotomyJoint line obliquityKnee osteoarthritisMechanical axis alignment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.