ArticleJournal of Korean medical science2025
Interstitial Lung Abnormality in Health Screening Examinees: Prevalence, Outcomes, and Risk Factors.
Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Current diagnosis, epidemiology, and management of interstitial lung abnormalities.Frontiers in medicine · 2026Review
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5 authors.
Funding
Abstract
backgroundThe prevalence, outcome and risk factors of interstitial lung abnormality (ILA) in the Asian population remains unclear.
methodsWe retrospectively enrolled participants who had health check-up and undergone serial chest computed tomography (CT) more than 5 years apart from baseline. The presence of ILA, as well as the temporal changes, was evaluated. Multivariable logistic regression was used to assess baseline risk factors associated with the progressive ILA (defined as development or progression of equivocal ILA or ILA) upon follow-up.
resultsIn total, 2,589 participants with a mean baseline age of 49 years (57 years upon follow-up scans) and a median follow-up of 7.0 years were included. We found that the prevalence of ILA or equivocal ILA increased between baseline and follow-up (baseline: 0.2% and 0.3%, respectively; follow-up: 0.8% and 0.9%, respectively) (
conclusionThe prevalence of ILA in middle-aged Korean health screening participants was relatively low but increased with age, with its presence associated with long-term impacts on mortality. Radiologic progression on ILA at baseline was common. Risk factors for progressive ILA, such as age, smoking history, and elevated inflammatory markers, were identified. These findings emphasize the importance of early identification and monitoring of ILA in at-risk populations to improve long-term outcomes.
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