Evidence map›Paper›PMID 40985747›Full record

ArticleBrain : a journal of neurology2025

Covert consciousness: what's in a name?

Charlène Aubinet, Jan Claassen, Brian L Edlow, David Fischer, Olivia Gosseries, Christof Koch, Daniel Kondziella, Marcello Massimini, Michael J Young

Abstract read
In one paragraph

Article in Brain : a journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Ethical Considerations in Transcranial Focused Ultrasound Neuromodulation for Disorders of Consciousness.Neuromodulation : journal of the International Neuromodulation Society · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charlène AubinetComa Science Group, GIGA Institute, University of Liège, Liège 4000, Belgium.ORCID 0000-0001-5095-5583
Jan ClaassenDisorders of Consciousness Laboratory, Columbia University Irving Medical Center, New York, NY 10032, USA.
Brian L EdlowDepartment of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0001-7235-8456
David FischerDepartment of Neurology, Recovery of Consciousness via Evidence-Based Medicine and Research (RECOVER) Program, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, Philadelphia 19104, USA.ORCID 0000-0001-8181-0643
Olivia GosseriesComa Science Group, GIGA Institute, University of Liège, Liège 4000, Belgium.
Christof KochBrain & Consciousness, Allen Institute, Seattle, WA 98109, USA.ORCID 0000-0001-6482-8067
Daniel KondziellaDepartment of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen 2100, Denmark.ORCID 0000-0001-5562-9808
Marcello MassiminiDepartment of Biomedical & Clinical Sciences, University of Milan, Milan 20157, Italy.
Michael J YoungDepartment of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0001-6661-0811

Funding

Promoting Recovery from Brain Injury with Non-Invasive Thalamic UltrasoundK23NS140495 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Michael J Young · 2025 to 2026
$469k
NINDS NIH HHS K23 NS140495
6 · The paper itself

Abstract

Over the past decade, it has become apparent that up to 25% of behaviourally unresponsive patients with acute or chronic disorders of consciousness reveal high spatio-temporal complexity following a direct electrical or magnetic pulse to the brain, highly differentiated EEG responses or voluntary modulation of their brain activity on command, each of which has been interpreted, to varying degrees, as evidence of consciousness. Practitioners designate this phenomenon using a dizzying variety of terms. The realization that 'unresponsiveness' does not equate to 'unconsciousness' changes how patients should be assessed and how the medical team communicates with them, their families and the world at large. We propose that the term 'covert consciousness' be used in all such communications to designate this subcategory of behaviourally unresponsive patients, with context-appropriate qualifiers and counselling accompanying its use.

Indexed as

ConsciousnessConsciousness DisordersTerminology as TopicBrainElectroencephalographyHumanscognitive motor dissociationcortically mediated statecovert awarenesscovert brain complexityfunctional locked-in syndromenon-behavioural minimally conscious state

Identifiers

PMID40985747
PMCPMC12677022

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.