Evidence map›Paper›PMID 40985635›Full record

ArticleApplied and environmental microbiology2025

DNA adenine methylation influences gene expression and biofilm formation in

Haowei Zhao, Delphine Dufour, Niki Ghobaei, Laurent Bozec, Céline M Lévesque

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Epigenomics identifies three sources of DNA methylation inbioRxiv : the preprint server for biology · 2026
    Article
  3. Membrane Vesicles ImproveMicroorganisms · 2026
    Article
  4. How to Unmask an Unknown: The Restriction-Modification SystemInternational journal of molecular sciences · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haowei ZhaoFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-0134-6495
Delphine DufourFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-1386-9595
Niki GhobaeiFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
Laurent BozecFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
Céline M LévesqueFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-8044-7141

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2019-06454
6 · The paper itself

Abstract

IMPORTANCE: This study highlights the critical role of DNA methylation in regulating biofilm formation and virulence in

Indexed as

AdenineBiofilmsDNA MethylationGene Expression Regulation, BacterialStreptococcus mutansBacterial ProteinsQuorum SensingAdenineBacterial Proteinsadenine methylationbiofilmextracellular DNAmembrane vesiclerestriction-modification systemStreptococcus mutans

Identifiers

PMID40985635
PMCPMC12542736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.