ArticleDialogues in clinical neuroscience2025
A long shot? Affective temperaments predict adherence to pharmacotherapy during infertility treatment in a prospective longitudinal study.
Article in Dialogues in clinical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionResearch suggests that affective temperaments influence adherence to pharmacotherapy; however, this has not been investigated in infertility treatment. Our prospective longitudinal study assessed the impact of affective temperaments on medication adherence during infertility treatments.
methods179 women presenting at an Assisted Reproduction Centre completed the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego (TEMPS-A) questionnaire before treatment, and the Morisky Medication Adherence Scale (MMAS) six months later. Univariate linear regression assessed whether affective temperaments predict medication adherence; multivariate and interaction models examined the influence of sociodemographic and medical variables on this relationship, and potential moderating effects of age and education.
resultsHigher cyclothymic, depressive, irritable, and anxious affective temperament scores predicted significantly poorer adherence to pharmacotherapeutic recommendations (
conclusionsAffective temperaments impact adherence to pharmacotherapeutic recommendations among women experiencing infertility, possibly influencing treatment outcomes. Screening for affective temperaments can identify patients at risk of medication non-adherence. Applying patient-tailored psychological interventions to aid adherence could increase the chances of successful pregnancies.
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