Evidence map›Paper›PMID 40985459›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2025

Development and application of desiderata for automated clinical ordering.

Sameh N Saleh, Kevin B Johnson

Abstract readValidation Study
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sameh N SalehDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.ORCID 0000-0001-5959-1659
Kevin B JohnsonDepartment of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA 19146, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAutomation of clinical orders in electronic health records (EHRs) has the potential to reduce clinician burden and enhance patient safety. However, determining which orders are appropriate for automation requires a structured framework to ensure clinical validity, transparency, and safety.

objectiveTo develop and validate a framework of desiderata for assessing the appropriateness of automating clinical orders in EHRs and to demonstrate its operational value in a live health system dataset. MATERIALS AND

methodsThe study comprised 4 phases to move from concept generation to real-world demonstration. First, we conducted focus group analyses using ground theory to identify themes and developed desiderata informed by these themes and existing literature. We validated the desiderata by surveying clinicians at a single institution, presenting 10 use cases to and assessing perceived appropriateness, cognitive support, and patient safety using a 4-point Likert scale. Survey results were compared to a priori appropriateness designations using t-tests. To evaluate operational impact, we analyzed one year of order-based alerts and orders (1.4 million firings alert and 44.1 million orders, respectively) using filtering rules and association rule mining to identify candidate orders for automation and their impact.

resultsWe identified 8 desiderata for automated order appropriateness: logical consistency, data provenance, order transparency, context permanence, monitoring plans, trigger consistency, care team empowerment, and system accountability. Use cases deemed appropriate based on these criteria received significantly higher scores for appropriateness (3.13 ± 0.84 vs 2.30 ± 0.99), cognitive support (3.08 ± 0.82 vs 2.25 ± 0.94), and patient safety (3.08 ± 0.86 vs 2.21 ± 0.98) (all P < .001) compared to those considered inappropriate. Operational analysis revealed an alert firing 19 109 times annually, with a 96% signed order rate, where automation could save an estimated 26.5 provider hours per year. Additionally, an association rule with 16 628 occurrences (68.4% confidence) suggested automation could save 15.8 hours annually and yield 8000 additional appropriate orders. DISCUSSION: The desiderata align with clinician perceptions and provide a structured approach for evaluating automated orders. Our findings highlight the potential for automation of certain clinical orders to improve cognitive support while maintaining patient safety.

conclusionHealthcare systems should use these desiderata, coupled with data mining techniques, to systematically identify and govern appropriate automated orders. Further research is needed to validate operational scalability.

Indexed as

Electronic Health RecordsMedical Order Entry SystemsAutomationFocus GroupsHumansPatient Safetyautomationclinical decision support systemsdata miningelectronic health recordsmedical order entry systemsworkflow

Identifiers

PMID40985459
PMCPMC12646375

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.