ArticleMovement disorders clinical practice2026
Integrity of Brainstem Connections in Essential Tremor Using Auditory and Vestibular Evoked Potentials.
Article in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEssential tremor (ET) is associated with various of non-motor symptoms including hearing impairment and imbalance attributed to the neurodegenerative ET pathology affecting brainstem structures.
objectiveThis study aimed to assess auditory and vestibular brainstem functions in patients with ET in comparison to controls using auditory brainstem responses (ABR) and cervical and ocular vestibular-evoked myogenic potentials (cVEMP and oVEMP), and to correlate their dysfunction to disease characteristics.
methods24 patients (48 ears) with ET and 24 healthy controls were recruited and assessed by ABR, cVEMP and oVEMP. Patients were assessed by Fahn-Tolosa-Marin Tremor Rating Scale (FTM-TRS) and functional gait assessment scale.
resultsHigh-rate ABR showed significant increase of waves III and V latencies and I-V interpeak latencies among patients, compared to age and gender matched controls. Low-rate ABR showed less significant differences; right, I-III and I-V interpeak latencies, and average I-III interlatences. ET patients showed prolonged latencies of P1 and N1 waves of cVEMP (P = 0.007 and P = 0.003), average P1-N1 latency and amplitude differences (P < 0.001) and P1 latency of oVEMP (P = 0.009), compared to controls, with more differences in cVEMP than in oVEMP. Age, age of onset, disease duration showed correlations with ABR responses, tremor severity correlated with oVEMP, while functional gait scores correlated with both.
conclusionThe study confirmed and localized the dysfunction of the auditory and vestibular brainstem connections in ET and demonstrated a possible correlation with tremor severity and associated gait dysfunction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.