Evidence map›Paper›PMID 40985021›Full record

ArticleSurgical case reports2025

Esophageal Bypass Surgery for an Esophagobronchial Fistula Following Palliative Irradiation for Left Main Bronchial Obstruction Caused by Mediastinal Malignant Lymphoma.

Byonggu An, Tetsuya Abe, Yasumitsu Oe, Yuki Morimoto, Yuuki Imazato, Hibiki Kanda, Katsunori Tai, Hiroki Fujita, Toru Imagami, Takeshi Togawa and 5 more

Abstract readCase Reports
In one paragraph

Article in Surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Byonggu AnDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.
Tetsuya AbeDepartment of Gastroenterological Surgery, Aichi Cancer Center Central Hospital, Nagoya, Aichi, Japan.
Yasumitsu OeDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.
Yuki MorimotoDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.
Yuuki ImazatoDepartment of Respiratory Medicine, Omi Medical Center, Kusatsu, Shiga, Japan.
Hibiki KandaDepartment of Respiratory Medicine, Omi Medical Center, Kusatsu, Shiga, Japan.
Katsunori TaiDepartment of Hematology, Omi Medical Center, Kusatsu, Shiga, Japan.
Hiroki FujitaDepartment of Gastroenterology, Omi Medical Center, Kusatsu, Shiga, Japan.
Toru ImagamiDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.
Takeshi TogawaDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.
Nobuyuki TakaoDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.
Akira SogawaDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.
Takashi MatsunagaDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.
Shizuki TakemuraDepartment of Diagnostic Pathology, Omi Medical Center, Kusatsu, Shiga, Japan.
Akiyoshi MizumotoDepartment of Digestive Surgery, Omi Medical Center, Kusatsu, Shiga, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCentral airway obstruction (CAO) due to malignancy is an oncological emergency that requires prompt management. On the other hand, esophagobronchial fistula (EBF) is also a serious condition that can lead to aspiration pneumonia and difficulty with oral intake. Secondary involvement due to malignant lymphoma is a very rare cause of both CAO and EBF. Here, we report a case of esophageal bypass surgery for an EBF that became apparent after palliative irradiation for left main bronchial obstruction caused by mediastinal malignant lymphoma. CASE PRESENTATION: A 76-year-old man was referred to our hospital with a chief complaint of dyspnea and dysphagia. Contrast-enhanced chest CT revealed a 10-cm irregularly shaped space-occupying lesion (SOL) in the middle mediastinum, involving the left main bronchus and esophagus. The left main bronchus was obstructed by the SOL, and the presence of gas within the lesion suggested the formation of a fistula between the tumor and the bronchus. Bronchoscopy revealed almost complete obstruction of the left main bronchus due to an ulcerative tumor. Upper gastrointestinal endoscopy revealed a deeply excavated esophageal ulcer, raising suspicion of a fistulous connection with the tumor. Although fistula formation between the tumor and the bronchus and/or esophagus was suspected, due to the oncological emergency of CAO presumably caused by mediastinal-type lung cancer, palliative irradiation and intravenous administration of betamethasone sodium phosphate were initiated prior to obtaining a pathological diagnosis. The tumor shrank remarkably after the treatment. However, as the tumor regressed, an EBF became apparent. Given the patient's strong desire to resume oral intake and the need for a definitive diagnosis, we planned a surgical intervention (esophageal bypass surgery with lymph node sampling). The patient's postoperative course was uneventful. He resumed oral intake on POD 9, and was discharged on day 20. Histopathological examination of the lymph nodes revealed diffuse large B-cell lymphoma. The patient began chemotherapy for malignant lymphoma 2 months after surgery.

conclusionsEsophageal bypass surgery is a valuable option for patients with an EBF, as it improves QOL and enables subsequent chemotherapy.

Indexed as

central airway obstruction (CAO)esophageal bypass surgeryesophagobronchial fistula (EBF)palliative radiotherapy

Identifiers

PMID40985021
PMCPMC12450555

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