ArticleInternational journal of women's health2025
Clinical Application of Noninvasive Prenatal Testing in Singleton Pregnancy with and without in vitro Fertilization: A 6-year Observational Study at a Single Tertiary Center.
Qian Zhang, Yuhong Guo, Bin Liang, Meihuan Chen, Xiaoqing Wu, Na Lin, Hailong Huang, Liangpu Xu
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In one paragraphArticle in International journal of women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Qian Zhang *Department of Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350001, People's Republic of China.ORCID 0000-0003-4311-967X Yuhong Guo *Department of Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350001, People's Republic of China.
Bin LiangDepartment of Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350001, People's Republic of China.ORCID 0000-0001-7659-3349 Meihuan ChenDepartment of Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350001, People's Republic of China.ORCID 0000-0002-7356-8751 Xiaoqing WuDepartment of Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350001, People's Republic of China.ORCID 0000-0003-2605-2362 Na LinDepartment of Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350001, People's Republic of China.
Hailong HuangDepartment of Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350001, People's Republic of China.ORCID 0000-0003-2924-399X Liangpu XuDepartment of Medical Genetic Diagnosis and Therapy Center, Fujian Key Laboratory for Prenatal Diagnosis and Birth Defect, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, 350001, People's Republic of China.ORCID 0000-0001-8815-2735 Funding
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6 · The paper itselfAbstract
Background: Studies on the use of noninvasive prenatal testing (NIPT) in pregnancies conceived by in vitro fertilization (IVF) remain inadequate. This study aimed to evaluate the performance of NIPT in singleton pregnancies conceived by IVF and to compare it with that in naturally conceived (NC) pregnancies. Methods: A retrospective analysis was performed on 86397 pregnancies (IVF=3723, NC=82674). The performance of NIPT was assessed by calculating the sensitivity, specificity, and positive predictive value (PPV). Results: The failure rate in the IVF group was significantly higher than that in the NC group (0.16% vs 0.04%, Conclusion: Our findings suggest that NIPT is a valid technique for detecting fetal chromosomal aneuploidies in IVF singleton pregnancies.
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IVFkinetics of fetal fractionsnatural conceptionNIPTperformance
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PMID40985009
PMCPMC12450383
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