Evidence map›Paper›PMID 40984961›Full record

ReviewCureus2025

Clinical Impact of Nasal Obstructive Syndrome and Its Current Management Strategies.

Freddy Lizano Guevara, Alberto Rojas Peláez, Edgardo J Soto-Junco, David Sáenz Araya, Enmanuel Sevilla Torres, Santiago Daniel Baizan Orias

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Freddy Lizano GuevaraGeneral Medicine, Universidad de Ciencias Médicas (UCIMED), San José, CRI.
Alberto Rojas PeláezGeneral Medicine, Universidad de Ciencias Médicas (UCIMED), San José, CRI.
Edgardo J Soto-JuncoGeneral Medicine, Universidad de Costa Rica, San José, CRI.
David Sáenz ArayaGeneral Medicine, Universidad de Ciencias Médicas (UCIMED), San José, CRI.
Enmanuel Sevilla TorresGeneral Medicine, Universidad de Ciencias Médicas (UCIMED), San José, CRI.
Santiago Daniel Baizan OriasGeneral Medicine, Universidad de Ciencias Médicas (UCIMED), San José, CRI.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasal obstruction syndrome (NOS) is inherently complex due to the combination of nasal anatomy and physiology and pathophysiologic processes that together affect airflow, filtering, smell, and the general health of the respiratory system. The nasopharynx consists of different structures together: the septum, turbinates, and nasal valves that together perform the jobs associated with the nasal polyp, which is to regulate air conditioning and mucociliary clearance. Changes that can be recognized in the septum, turbinates, and nasal valve will individually and/or collectively affect the potential for airway obstruction. However, obstructions may not occur as a function of anatomy; they may occur via anatomical functional restrictions, as is believed to be the case with breathing-facilitating trigeminal nerve dysfunction, evidenced by the subjective sensations of nasal obstruction while no anterior nasal obstruction is observed. In addition to anatomical changes such as turbinate hypertrophy, outpt septal deviation, and/or nasal valve collapse, there are also chronic inflammatory disease states such as rhinosinusitis, allergic and non-allergic rhinitis, and nasal polyposis that will develop to produce nasal obstructions via mucosal edema and structural room through tissue remodeling. The clinical consequence of NOS is nasal airway congestion, hyposmia, and compensatory mouth breathing, with the latter two activities causing harm to sensory deficits such as taste, sleep quality, and cognitive functioning, and impedance in health-related quality of life. Commonly utilized diagnostic procedures include nasal endoscopy, CT, and testing for the effects of nasal obstruction (e.g., the Nasal Obstruction Symptom Evaluation (NOSE) scale, Sino-Nasal Outcome Test-22 (SNOT-22), and Visual Analog Scale (VAS)), which are specific to confirm the effect of nasal obstruction. Radiological and nasal endoscopic findings focused on anatomical distortions and specific patterns of obstructive nasal difficulty, particularly in chronic, difficult-to-treat rhinosinusitis and nasal valve obstruction. Management plans unite both pharmacologic options, such as antihistamines, corticosteroids, and immunotherapies, with surgical procedures, which can include septoplasty, turbinate reduction, nasal valve reconstruction, and functional endoscopic sinus surgery (FESS). Treatment will depend on the patient's specific medical and social history, which is especially critical for children, older-age patients, and patients with comorbid respiratory problems such as asthma or obstructive sleep apnea (OSA). For children, the typical catalyst for nasal obstruction appears to be adenoid hypertrophy, whereas older patients may differ in their nasal microbiota. Management is a multidisciplinary team effort, engaging otolaryngology, allergy, and pulmonology specialists to treat this multifaceted condition.

Indexed as

allergicnasal obstructionnasal obstruction syndromeobstructive sleep apneaparanasal sinusesquality of liferhinitis

Identifiers

PMID40984961
PMCPMC12450431

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.