Evidence map›Paper›PMID 40984900›Full record

ReviewCureus2025

Microbiota-Based Therapies for Recurrent Clostridium difficile Infection: A Systematic Review of Their Efficacy and Safety.

Sasika Weerakoon, Sravanthi Avula, Bethel T Mandefro, Sri Vidya Sundara, Xinyu Lu, Hamide Busmail, Iana A Malasevskaia

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sasika WeerakoonInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sravanthi AvulaPediatrics, NRI Medical College, Guntur, IND.
Bethel T MandefroMedicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Sri Vidya SundaraPediatrics, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Xinyu LuENT, Shanghai Pudong Hospital, Shanghai, CHN.
Hamide BusmailInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Iana A MalasevskaiaHospital-Based Medicine, Harvard T.H. Chan School of Public Health, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent

Indexed as

fecal microbiota transplantation (fmt)gut dysbiosislive biotherapeutic productsmicrobiome-based therapiesrecurrent clostridioides difficile infection (rcdi)

Identifiers

PMID40984900
PMCPMC12450354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.